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Psme3ip1 proteasome activator subunit 3 interacting protein 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307652, updated on 10-Jul-2024

Summary

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Official Symbol
Psme3ip1provided by RGD
Official Full Name
proteasome activator subunit 3 interacting protein 1provided by RGD
Primary source
RGD:1307433
See related
EnsemblRapid:ENSRNOG00000017841 AllianceGenome:RGD:1307433
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Nip30; Fam192a; RGD1307433
Summary
Predicted to be involved in negative regulation of proteasomal protein catabolic process and negative regulation of protein binding activity. Predicted to be active in nucleus. Orthologous to human PSME3IP1 (proteasome activator subunit 3 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 133.9), Thymus (RPKM 113.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Psme3ip1 in Genome Data Viewer
Location:
19p13
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (10407382..10436029)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (10401400..10430059)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (10827057..10856747)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene plasmolipin Neighboring gene ADP-ribosylation factor like GTPase 2 binding protein Neighboring gene ring finger and SPRY domain containing 1 Neighboring gene small nucleolar RNA SNORA5 Neighboring gene uncharacterized LOC134483687 Neighboring gene copine 2 Neighboring gene uncharacterized LOC134483689

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28γ. Jonik-Nowak B, et al. Proc Natl Acad Sci U S A, 2018 Jul 10. PMID 29934401, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in negative regulation of proteasomal protein catabolic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
PSME3-interacting protein
Names
NEFA-interacting nuclear protein NIP30
family with sequence similarity 192, member A
protein FAM192A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014014.1 → NP_001014036.1  PSME3-interacting protein

    See identical proteins and their annotated locations for NP_001014036.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079145
    UniProtKB/TrEMBL
    F7EUG6, Q6AY90
    Related
    ENSRNOP00000024120.6, ENSRNOT00000024120.7
    Conserved Domains (1) summary
    pfam10187
    Location:15 → 98
    Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    10407382..10436029
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039097714.2 → XP_038953642.1  PSME3-interacting protein isoform X1

    UniProtKB/TrEMBL
    F7EUG6, Q6AY90
    Conserved Domains (1) summary
    pfam10187
    Location:15 → 98
    Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

  2. XM_063277993.1 → XP_063134063.1  PSME3-interacting protein isoform X1

    UniProtKB/TrEMBL
    F7EUG6, Q6AY90

  3. XM_039097712.2 → XP_038953640.1  PSME3-interacting protein isoform X1

    UniProtKB/TrEMBL
    F7EUG6, Q6AY90
    Conserved Domains (1) summary
    pfam10187
    Location:15 → 98
    Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

  4. XM_063277992.1 → XP_063134062.1  PSME3-interacting protein isoform X1

    UniProtKB/TrEMBL
    F7EUG6, Q6AY90

  5. XM_063277991.1 → XP_063134061.1  PSME3-interacting protein isoform X1

    UniProtKB/TrEMBL
    F7EUG6, Q6AY90
    Related
    ENSRNOP00000103465.1, ENSRNOT00000128462.1

  6. XM_006255110.4 → XP_006255172.1  PSME3-interacting protein isoform X1

    See identical proteins and their annotated locations for XP_006255172.1

    UniProtKB/TrEMBL
    F7EUG6, Q6AY90
    Conserved Domains (1) summary
    pfam10187
    Location:15 → 98
    Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

  7. XM_063277994.1 → XP_063134064.1  PSME3-interacting protein isoform X1

    UniProtKB/TrEMBL
    F7EUG6, Q6AY90

  8. XM_039097711.2 → XP_038953639.1  PSME3-interacting protein isoform X1

    UniProtKB/TrEMBL
    F7EUG6, Q6AY90
    Conserved Domains (1) summary
    pfam10187
    Location:15 → 98
    Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

  9. XM_006255111.3 → XP_006255173.1  PSME3-interacting protein isoform X1

    See identical proteins and their annotated locations for XP_006255173.1

    UniProtKB/TrEMBL
    F7EUG6, Q6AY90
    Conserved Domains (1) summary
    pfam10187
    Location:15 → 98
    Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

  10. XM_017601276.3 → XP_017456765.1  PSME3-interacting protein isoform X1

    UniProtKB/TrEMBL
    F7EUG6, Q6AY90
    Conserved Domains (1) summary
    pfam10187
    Location:15 → 98
    Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
Nucleotide Protein Strain
Heading Accession and Version

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