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stat1a - signal transducer and activator of transcription 1a

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; regulation of transcription by RNA polymerase II; and response to peptide hormone. Predicted to act upstream of or within regulation of transcription, DNA-templated and signal transduction. Predicted to be located in cytoplasm and nucleus. Is expressed in blood; kidney; and spleen. Human ortholog(s) of this gene implicated in breast cancer (multiple); immunodeficiency 31A; immunodeficiency 31B; immunodeficiency 31C; and prostate adenocarcinoma. Orthologous to human STAT1 (signal transducer and activator of transcription 1). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa