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Atrnl1 attractin like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307992, updated on 2-Nov-2024

Summary

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Official Symbol
Atrnl1provided by RGD
Official Full Name
attractin like 1provided by RGD
Primary source
RGD:1563485
See related
EnsemblRapid:ENSRNOG00000017406 AllianceGenome:RGD:1563485
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563485
Summary
Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Orthologous to human ATRNL1 (attractin like 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 427.0), Brain (RPKM 323.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Atrnl1 in Genome Data Viewer
Location:
1q55
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (266676051..267216847)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (256670976..257219291)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (278546113..279098977)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551125 Neighboring gene uncharacterized LOC134485260 Neighboring gene ribosomal protein S19, pseudogene 14 Neighboring gene uncharacterized LOC134485261 Neighboring gene uncharacterized LOC120097692 Neighboring gene uncharacterized LOC108349828 Neighboring gene uncharacterized LOC102556644 Neighboring gene GDNF family receptor alpha 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Melanocortin receptors and their accessory proteins. Cooray SN, et al. Mol Cell Endocrinol, 2011 Jan 15. PMID 20654690
  2. Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein. Haqq AM, et al. Biochem J, 2003 Dec 15. PMID 14531729, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
attractin like 1; attractin-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431114.1 → NP_001418043.1  attractin like 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A8I5Y1Z3

  2. NM_001431115.1 → NP_001418044.1  attractin like 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    266676051..267216847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008760587.4 → XP_008758809.2  attractin-like protein 1 isoform X1

    Related
    ENSRNOP00000078125.1, ENSRNOT00000118477.2
    Conserved Domains (8) summary
    PLN02153
    Location:349 → 615
    PLN02153; epithiospecifier protein
    cd00041
    Location:92 → 207
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00055
    Location:1011 → 1056
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:520 → 573
    Kelch; KELCH repeat [structural motif]
    pfam01437
    Location:887 → 936
    PSI; Plexin repeat
    pfam13854
    Location:351 → 391
    Kelch_5; Kelch motif
    cl02432
    Location:746 → 872
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl19567
    Location:234 → 279
    DSL; Delta serrate ligand

  2. XM_039095274.2 → XP_038951202.1  attractin-like protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I6AGE2, F1M3T8
    Related
    ENSRNOP00000087353.1, ENSRNOT00000111371.2
    Conserved Domains (8) summary
    PLN02153
    Location:349 → 615
    PLN02153; epithiospecifier protein
    cd00041
    Location:92 → 207
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00055
    Location:1011 → 1056
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:520 → 573
    Kelch; KELCH repeat [structural motif]
    pfam01437
    Location:887 → 936
    PSI; Plexin repeat
    pfam13854
    Location:351 → 391
    Kelch_5; Kelch motif
    cl02432
    Location:746 → 872
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl19567
    Location:234 → 279
    DSL; Delta serrate ligand

  3. XM_063281046.1 → XP_063137116.1  attractin-like protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZVB8

  4. XM_039095277.2 → XP_038951205.1  attractin-like protein 1 isoform X4

    UniProtKB/TrEMBL
    F1M3T8
    Related
    ENSRNOP00000023414.8, ENSRNOT00000023414.9
    Conserved Domains (8) summary
    PLN02153
    Location:349 → 615
    PLN02153; epithiospecifier protein
    cd00041
    Location:92 → 207
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00055
    Location:1011 → 1056
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:520 → 573
    Kelch; KELCH repeat [structural motif]
    pfam01437
    Location:887 → 936
    PSI; Plexin repeat
    pfam13854
    Location:351 → 391
    Kelch_5; Kelch motif
    cl02432
    Location:746 → 872
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl19567
    Location:234 → 279
    DSL; Delta serrate ligand

  5. XM_039095283.2 → XP_038951211.1  attractin-like protein 1 isoform X5

    Conserved Domains (8) summary
    cd03597
    Location:601 → 727
    CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
    PLN02153
    Location:204 → 470
    PLN02153; epithiospecifier protein
    cd00055
    Location:866 → 911
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:375 → 428
    Kelch; KELCH repeat [structural motif]
    pfam01437
    Location:742 → 791
    PSI; Plexin repeat
    pfam13854
    Location:206 → 246
    Kelch_5; Kelch motif
    cl00049
    Location:3 → 62
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cl19567
    Location:89 → 134
    DSL; Delta serrate ligand
Nucleotide Protein Strain
Heading Accession and Version

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