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Fam120b family with sequence similarity 120 member B [ Rattus norvegicus (Norway rat) ]

Gene ID: 308218, updated on 2-Nov-2024

Summary

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Official Symbol
Fam120bprovided by RGD
Official Full Name
family with sequence similarity 120 member Bprovided by RGD
Primary source
RGD:1310304
See related
EnsemblRapid:ENSRNOG00000058790 AllianceGenome:RGD:1310304
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310304
Summary
Predicted to be involved in fat cell differentiation and peroxisome proliferator activated receptor signaling pathway. Predicted to be active in nucleus. Orthologous to human FAM120B (family with sequence similarity 120 member B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 124.1), Kidney (RPKM 86.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fam120b in Genome Data Viewer
Location:
1q12
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (64993104..65058160)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (56320015..56385064)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (57345559..57392114)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102550720 Neighboring gene uncharacterized LOC134485093 Neighboring gene ribosomal protein SA, pseudogene 16 Neighboring gene delta like canonical Notch ligand 1 Neighboring gene uncharacterized LOC102557016 Neighboring gene proteasome 20S subunit beta 1 Neighboring gene TATA box binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in fat cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within fat cell differentiation ISO
Inferred from Sequence Orthology
more info
  
involved_in peroxisome proliferator activated receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within peroxisome proliferator activated receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
constitutive coactivator of peroxisome proliferator-activated receptor gamma
Names
family with sequence similarity 120B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107466.4 → NP_001100936.2  constitutive coactivator of peroxisome proliferator-activated receptor gamma

    See identical proteins and their annotated locations for NP_001100936.2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A0G2K8J8, A6KB41, D4AE88
    Related
    ENSRNOP00000069852.2, ENSRNOT00000084017.3
    Conserved Domains (1) summary
    cd18672
    Location:5 → 213
    PIN_FAM120B-like; FEN-like PIN domains of FAM120B (family with sequence similarity 120B) and related proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    64993104..65058160
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039110798.2 → XP_038966726.1  constitutive coactivator of peroxisome proliferator-activated receptor gamma isoform X1

    UniProtKB/TrEMBL
    A0A0G2K8J8, A6KB41, D4AE88
    Conserved Domains (1) summary
    cd18672
    Location:5 → 213
    PIN_FAM120B-like; FEN-like PIN domains of FAM120B (family with sequence similarity 120B) and related proteins

  2. XM_039110806.2 → XP_038966734.1  constitutive coactivator of peroxisome proliferator-activated receptor gamma isoform X1

    UniProtKB/TrEMBL
    A0A0G2K8J8, A6KB41, D4AE88
    Related
    ENSRNOP00000107565.1, ENSRNOT00000133470.1
    Conserved Domains (1) summary
    cd18672
    Location:5 → 213
    PIN_FAM120B-like; FEN-like PIN domains of FAM120B (family with sequence similarity 120B) and related proteins

  3. XM_039110803.2 → XP_038966731.1  constitutive coactivator of peroxisome proliferator-activated receptor gamma isoform X1

    UniProtKB/TrEMBL
    A0A0G2K8J8, A6KB41, D4AE88
    Conserved Domains (1) summary
    cd18672
    Location:5 → 213
    PIN_FAM120B-like; FEN-like PIN domains of FAM120B (family with sequence similarity 120B) and related proteins

  4. XM_039110811.2 → XP_038966739.1  constitutive coactivator of peroxisome proliferator-activated receptor gamma isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZXF7
    Conserved Domains (1) summary
    cd18672
    Location:5 → 213
    PIN_FAM120B-like; FEN-like PIN domains of FAM120B (family with sequence similarity 120B) and related proteins

  5. XM_039110812.2 → XP_038966740.1  constitutive coactivator of peroxisome proliferator-activated receptor gamma isoform X3

    UniProtKB/TrEMBL
    A0A0G2K8J8, A0A8I6A0B3
    Related
    ENSRNOP00000083603.1, ENSRNOT00000118789.2
    Conserved Domains (1) summary
    cd18672
    Location:5 → 213
    PIN_FAM120B-like; FEN-like PIN domains of FAM120B (family with sequence similarity 120B) and related proteins

  6. XM_063288585.1 → XP_063144655.1  constitutive coactivator of peroxisome proliferator-activated receptor gamma isoform X4

  7. XM_063288575.1 → XP_063144645.1  constitutive coactivator of peroxisome proliferator-activated receptor gamma isoform X1

    UniProtKB/TrEMBL
    A6KB41, D4AE88

  8. XM_039110817.2 → XP_038966745.1  constitutive coactivator of peroxisome proliferator-activated receptor gamma isoform X5

RNA

  1. XR_005504540.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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