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Fbxo30 F-box protein 30 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308283, updated on 2-Nov-2024

Summary

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Official Symbol
Fbxo30provided by RGD
Official Full Name
F-box protein 30provided by RGD
Primary source
RGD:1359367
See related
EnsemblRapid:ENSRNOG00000014852 AllianceGenome:RGD:1359367
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Predicted to be involved in protein ubiquitination. Orthologous to human FBXO30 (F-box protein 30). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 214.3), Heart (RPKM 133.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fbxo30 in Genome Data Viewer
Location:
1p13
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (7475636..7491719)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (5655341..5671558)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (5366119..5389774)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene SNF2 histone linker PHD RING helicase Neighboring gene uncharacterized LOC102547024 Neighboring gene small nucleolar RNA, H/ACA box 70J Neighboring gene calponin-2-like Neighboring gene EPM2A glucan phosphatase, laforin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system. Ebstein F, et al. Int J Biochem Cell Biol, 2009 May. PMID 19028597
  2. RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1. Yuan L, et al. Cardiovasc Res, 2023 Mar 17. PMID 35352799
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC94907

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
F-box only protein 30

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007690.1 → NP_001007691.1  F-box only protein 30

    See identical proteins and their annotated locations for NP_001007691.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083823
    UniProtKB/Swiss-Prot
    Q5XI67
    UniProtKB/TrEMBL
    A6JP44
    Related
    ENSRNOP00000112091.1, ENSRNOT00000140474.1
    Conserved Domains (2) summary
    pfam15965
    Location:8 → 100
    zf-TRAF_2; TRAF-like zinc-finger
    pfam15966
    Location:610 → 718
    F-box_4; F-box

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    7475636..7491719
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006227640.5 → XP_006227702.1  F-box only protein 30 isoform X1

    See identical proteins and their annotated locations for XP_006227702.1

    UniProtKB/Swiss-Prot
    Q5XI67
    UniProtKB/TrEMBL
    A6JP44
    Related
    ENSRNOP00000019918.3, ENSRNOT00000019918.7
    Conserved Domains (2) summary
    pfam15965
    Location:8 → 100
    zf-TRAF_2; TRAF-like zinc-finger
    pfam15966
    Location:610 → 718
    F-box_4; F-box
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XI67.1 GenPept UniProtKB/Swiss-Prot:Q5XI67

Gene LinkOut

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