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Zfp667 zinc finger protein 667 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308326, updated on 28-Oct-2024

Summary

Official Symbol
Zfp667provided by RGD
Official Full Name
zinc finger protein 667provided by RGD
Primary source
RGD:1359114
See related
EnsemblRapid:ENSRNOG00000033906 AllianceGenome:RGD:1359114
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mip1; Znf667
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF667 (zinc finger protein 667). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in Brain (RPKM 46.1), Muscle (RPKM 39.7) and 9 other tissues See more
Orthologs
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Genomic context

See Zfp667 in Genome Data Viewer
Location:
1q12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (76634897..76655133, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (67601803..67622041, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (71270101..71290337, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134482884 Neighboring gene zinc finger protein 829 like, pseudogene 1 Neighboring gene zinc finger protein 583 Neighboring gene uncharacterized LOC134482883 Neighboring gene zinc finger and SCAN domain containing 5B

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 667
Names
myocardial ischemic preconditioning up-regulated protein 1
myocardial ischemic preconditioning upregulated 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008557.1NP_001008557.1  zinc finger protein 667

    See identical proteins and their annotated locations for NP_001008557.1

    Status: VALIDATED

    Source sequence(s)
    AY221750
    UniProtKB/Swiss-Prot
    Q5MYW4
    Related
    ENSRNOP00000061115.4, ENSRNOT00000063956.5
    Conserved Domains (5) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:141599
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:499519
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:456480
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    76634897..76655133 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006228189.4XP_006228251.1  zinc finger protein 667 isoform X1

    See identical proteins and their annotated locations for XP_006228251.1

    UniProtKB/Swiss-Prot
    Q5MYW4
    Conserved Domains (5) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:141599
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:499519
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:456480
    zf-H2C2_2; Zinc-finger double domain