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Ppp1r37 protein phosphatase 1, regulatory subunit 37 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308398, updated on 2-Nov-2024

Summary

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Symbol
Ppp1r37provided by RGD
Full Name
protein phosphatase 1, regulatory subunit 37provided by RGD
Primary source
RGD:1595870
See related
EnsemblRapid:ENSRNOG00000017692 AllianceGenome:RGD:1595870
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Lrrc68
Summary
Predicted to enable protein phosphatase inhibitor activity. Orthologous to human PPP1R37 (protein phosphatase 1 regulatory subunit 37). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 123.7), Brain (RPKM 118.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ppp1r37 in Genome Data Viewer
Location:
1q21
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (88308782..88340796, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (79180794..79212612, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (80439718..80471527, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 6A Neighboring gene NTPase, KAP family P-loop domain containing 1 Neighboring gene gem (nuclear organelle) associated protein 7 Neighboring gene zinc finger protein 296

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein phosphatase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein phosphatase 1 regulatory subunit 37
Names
leucine rich repeat containing 68
leucine-rich repeat-containing protein 68

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107482.1 → NP_001100952.1  protein phosphatase 1 regulatory subunit 37

    See identical proteins and their annotated locations for NP_001100952.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473979
    UniProtKB/Swiss-Prot
    B2RYF1
    UniProtKB/TrEMBL
    A0A8I6GE78
    Related
    ENSRNOP00000023866.5, ENSRNOT00000023867.8
    Conserved Domains (3) summary
    COG4886
    Location:248 → 453
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd00116
    Location:115 → 433
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:168 → 196
    LRR_RI; leucine-rich repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    88308782..88340796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063261305.1 → XP_063117375.1  protein phosphatase 1 regulatory subunit 37 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B2RYF1.1 GenPept UniProtKB/Swiss-Prot:B2RYF1

Gene LinkOut

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