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Samd4b sterile alpha motif domain containing 4B [ Rattus norvegicus (Norway rat) ]

Gene ID: 308473, updated on 2-Nov-2024

Summary

Official Symbol
Samd4bprovided by RGD
Official Full Name
sterile alpha motif domain containing 4Bprovided by RGD
Primary source
RGD:1305597
See related
EnsemblRapid:ENSRNOG00000079475 AllianceGenome:RGD:1305597
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305597
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within cerebellar neuron development. Predicted to be located in cytosol. Predicted to be active in P-body. Orthologous to human SAMD4B (sterile alpha motif domain containing 4B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 154.4), Lung (RPKM 82.3) and 9 other tissues See more
Orthologs
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Genomic context

See Samd4b in Genome Data Viewer
Location:
1q21
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (92816955..92855243, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (83689413..83728652, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (85324017..85362266)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 29 Neighboring gene PAF1 homolog, Paf1/RNA polymerase II complex component Neighboring gene glia maturation factor, gamma Neighboring gene leucine rich repeat and fibronectin type III domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables mRNA binding ISO
Inferred from Sequence Orthology
more info
 
enables translation repressor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cerebellar neuron development ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of translation IEA
Inferred from Electronic Annotation
more info
 
involved_in nuclear-transcribed mRNA poly(A) tail shortening IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107498.1NP_001100968.1  protein Smaug homolog 2

    See identical proteins and their annotated locations for NP_001100968.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473979
    UniProtKB/TrEMBL
    A6J9J0, D4A769
    Related
    ENSRNOP00000026839.4, ENSRNOT00000026839.6
    Conserved Domains (1) summary
    cd09557
    Location:296358
    SAM_Smaug; SAM domain of Smaug subfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    92816955..92855243 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063261540.1XP_063117610.1  protein Smaug homolog 2 isoform X2

  2. XM_008759143.4XP_008757365.1  protein Smaug homolog 2 isoform X1

    See identical proteins and their annotated locations for XP_008757365.1

    UniProtKB/TrEMBL
    A6J9J0, D4A769
    Related
    ENSRNOP00000076302.2, ENSRNOT00000093693.3
    Conserved Domains (1) summary
    cd09557
    Location:296358
    SAM_Smaug; SAM domain of Smaug subfamily
  3. XM_063261538.1XP_063117608.1  protein Smaug homolog 2 isoform X1

    UniProtKB/TrEMBL
    A6J9J0, D4A769