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Dpy19l3 dpy-19 like C-mannosyltransferase 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308519, updated on 18-Sep-2024

Summary

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Official Symbol
Dpy19l3provided by RGD
Official Full Name
dpy-19 like C-mannosyltransferase 3provided by RGD
Primary source
RGD:1308334
See related
EnsemblRapid:ENSRNOG00000021573 AllianceGenome:RGD:1308334
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308334
Summary
Predicted to enable mannosyltransferase activity. Predicted to be involved in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan. Predicted to be integral component of membrane. Predicted to be active in nuclear inner membrane. Orthologous to human DPY19L3 (dpy-19 like C-mannosyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Liver (RPKM 124.2), Kidney (RPKM 94.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Dpy19l3 in Genome Data Viewer
Location:
1q21
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (97487206..97554232, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (88350303..88417339, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (92002927..92069855, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 27 Neighboring gene programmed cell death 5 Neighboring gene uncharacterized LOC134483099 Neighboring gene zinc finger protein 507 Neighboring gene uncharacterized LOC134484890

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mannosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
probable C-mannosyltransferase DPY19L3
Names
dpy-19-like 3
protein dpy-19 homolog 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135835.2 → NP_001129307.2  probable C-mannosyltransferase DPY19L3

    See identical proteins and their annotated locations for NP_001129307.2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6JAC6, D4A9G5
    Related
    ENSRNOP00000033949.3, ENSRNOT00000039115.5
    Conserved Domains (1) summary
    pfam10034
    Location:57 → 712
    Dpy19; Q-cell neuroblast polarization

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    97487206..97554232 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006228888.5 → XP_006228950.1  probable C-mannosyltransferase DPY19L3 isoform X1

    See identical proteins and their annotated locations for XP_006228950.1

    UniProtKB/TrEMBL
    A6JAC6, D4A9G5
    Conserved Domains (1) summary
    pfam10034
    Location:57 → 712
    Dpy19; Q-cell neuroblast polarization

  2. XM_006228889.5 → XP_006228951.1  probable C-mannosyltransferase DPY19L3 isoform X1

    See identical proteins and their annotated locations for XP_006228951.1

    UniProtKB/TrEMBL
    A6JAC6, D4A9G5
    Conserved Domains (1) summary
    pfam10034
    Location:57 → 712
    Dpy19; Q-cell neuroblast polarization

  3. XM_008759164.4 → XP_008757386.1  probable C-mannosyltransferase DPY19L3 isoform X3

    UniProtKB/TrEMBL
    A6JAC6
    Conserved Domains (1) summary
    pfam10034
    Location:1 → 589
    Dpy19; Q-cell neuroblast polarization

  4. XM_017589127.3 → XP_017444616.1  probable C-mannosyltransferase DPY19L3 isoform X2

    UniProtKB/TrEMBL
    A6JAC6
    Conserved Domains (1) summary
    pfam10034
    Location:1 → 611
    Dpy19; Q-cell neuroblast polarization
Nucleotide Protein Strain
Heading Accession and Version

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