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Tmem86a transmembrane protein 86A [ Rattus norvegicus (Norway rat) ]

Gene ID: 308602, updated on 17-Aug-2024

Summary

Official Symbol
Tmem86aprovided by RGD
Official Full Name
transmembrane protein 86Aprovided by RGD
Primary source
RGD:1305749
See related
EnsemblRapid:ENSRNOG00000013663 AllianceGenome:RGD:1305749
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305749
Summary
Predicted to enable alkenylglycerophosphocholine hydrolase activity and alkenylglycerophosphoethanolamine hydrolase activity. Predicted to be integral component of membrane. Orthologous to human TMEM86A (transmembrane protein 86A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 496.7), Kidney (RPKM 277.8) and 8 other tissues See more
Orthologs
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Genomic context

See Tmem86a in Genome Data Viewer
Location:
1q22
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (106732168..106736518)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (97595910..97600260)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (103173032..103177382)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene SPT2 chromatin protein domain containing 1 Neighboring gene uncharacterized LOC134483110 Neighboring gene large ribosomal subunit protein eL8-like Neighboring gene immunoglobulin superfamily member 22 Neighboring gene protein tyrosine phosphatase, non-receptor type 5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables alkenylglycerophosphocholine hydrolase activity ISO
Inferred from Sequence Orthology
more info
 
enables hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
lysoplasmalogenase TMEM86A
Names
lysoplasmalogenase-like protein TMEM86A
NP_001128488.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135016.1NP_001128488.1  lysoplasmalogenase TMEM86A

    Status: VALIDATED

    Source sequence(s)
    AA924203, BE100466, BE109619, CO395066
    UniProtKB/TrEMBL
    A6JBE3, D3ZI62
    Related
    ENSRNOP00000018688.5, ENSRNOT00000018688.8
    Conserved Domains (1) summary
    pfam07947
    Location:37224
    YhhN; YhhN-like protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    106732168..106736518
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)