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Nipa2 NIPA magnesium transporter 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308667, updated on 17-Aug-2024

Summary

Official Symbol
Nipa2provided by RGD
Official Full Name
NIPA magnesium transporter 2provided by RGD
Primary source
RGD:1306051
See related
EnsemblRapid:ENSRNOG00000012690 AllianceGenome:RGD:1306051
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
SLC56A2; RGD1306051
Summary
Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in magnesium ion transport. Predicted to be located in early endosome and plasma membrane. Predicted to be active in membrane. Orthologous to human NIPA2 (NIPA magnesium transporter 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 147.2), Spleen (RPKM 146.2) and 9 other tissues See more
Orthologs
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Genomic context

Location:
1q22
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (115935759..115960034, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (106799979..106824206, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (114346005..114371907, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene NIPA magnesium transporter 1 Neighboring gene cytoplasmic FMR1 interacting protein 1 Neighboring gene U6 spliceosomal RNA Neighboring gene peroxiredoxin 3, pseudogene 1 Neighboring gene uncharacterized LOC108348727 Neighboring gene uncharacterized LOC134483328 Neighboring gene HECT and RLD domain containing E3 ubiquitin protein ligase 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables magnesium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in magnesium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in magnesium ion transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in magnesium ion transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in early endosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
magnesium transporter NIPA2
Names
non imprinted in Prader-Willi/Angelman syndrome 2 homolog
solute carrier family 56 member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107518.1NP_001100988.1  magnesium transporter NIPA2

    See identical proteins and their annotated locations for NP_001100988.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474036
    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
    Related
    ENSRNOP00000018028.3, ENSRNOT00000018028.6
    Conserved Domains (1) summary
    pfam05653
    Location:8302
    Mg_trans_NIPA; Magnesium transporter NIPA

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    115935759..115960034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006229295.5XP_006229357.1  magnesium transporter NIPA2 isoform X1

    See identical proteins and their annotated locations for XP_006229357.1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
    Conserved Domains (1) summary
    pfam05653
    Location:8302
    Mg_trans_NIPA; Magnesium transporter NIPA
  2. XM_006229297.5XP_006229359.1  magnesium transporter NIPA2 isoform X1

    See identical proteins and their annotated locations for XP_006229359.1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
    Conserved Domains (1) summary
    pfam05653
    Location:8302
    Mg_trans_NIPA; Magnesium transporter NIPA
  3. XM_006229298.5XP_006229360.1  magnesium transporter NIPA2 isoform X1

    See identical proteins and their annotated locations for XP_006229360.1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
    Conserved Domains (1) summary
    pfam05653
    Location:8302
    Mg_trans_NIPA; Magnesium transporter NIPA
  4. XM_063262371.1XP_063118441.1  magnesium transporter NIPA2 isoform X1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
  5. XM_039112506.2XP_038968434.1  magnesium transporter NIPA2 isoform X1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
    Conserved Domains (1) summary
    pfam05653
    Location:8302
    Mg_trans_NIPA; Magnesium transporter NIPA
  6. XM_017589153.3XP_017444642.1  magnesium transporter NIPA2 isoform X1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
    Conserved Domains (1) summary
    pfam05653
    Location:8302
    Mg_trans_NIPA; Magnesium transporter NIPA
  7. XM_017589154.3XP_017444643.1  magnesium transporter NIPA2 isoform X1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
    Conserved Domains (1) summary
    pfam05653
    Location:8302
    Mg_trans_NIPA; Magnesium transporter NIPA
  8. XM_063262383.1XP_063118453.1  magnesium transporter NIPA2 isoform X1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
  9. XM_006229292.5XP_006229354.1  magnesium transporter NIPA2 isoform X1

    See identical proteins and their annotated locations for XP_006229354.1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
    Conserved Domains (1) summary
    pfam05653
    Location:8302
    Mg_trans_NIPA; Magnesium transporter NIPA
  10. XM_063262375.1XP_063118445.1  magnesium transporter NIPA2 isoform X1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
  11. XM_063262372.1XP_063118442.1  magnesium transporter NIPA2 isoform X1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
  12. XM_006229296.5XP_006229358.1  magnesium transporter NIPA2 isoform X1

    See identical proteins and their annotated locations for XP_006229358.1

    UniProtKB/TrEMBL
    A6KD29, D3ZUV1
    Conserved Domains (1) summary
    pfam05653
    Location:8302
    Mg_trans_NIPA; Magnesium transporter NIPA