U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ttll13 tubulin tyrosine ligase like 13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308762, updated on 10-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
Ttll13provided by RGD
Official Full Name
tubulin tyrosine ligase like 13provided by RGD
Primary source
RGD:1310399
See related
EnsemblRapid:ENSRNOG00000056362 AllianceGenome:RGD:1310399
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310399
Summary
Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization and protein polyglutamylation. Predicted to be active in cilium. Orthologous to human TTLL13 (tubulin tyrosine ligase like 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 287.6), Thymus (RPKM 43.7) and 7 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Ttll13 in Genome Data Viewer
Location:
1q31
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (143601777..143622344)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (134197801..134213083)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (142034423..142050071)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene semaphorin 4B Neighboring gene calcium and integrin binding 1 Neighboring gene GDP-D-glucose phosphorylase 1 Neighboring gene neugrin, neurite outgrowth associated Neighboring gene VPS33B, late endosome and lysosome associated

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC189386

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tubulin-glutamic acid ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tubulin-glutamic acid ligase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in microtubule bundle formation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein modification process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
tubulin polyglutamylase TTLL13
Names
tubulin tyrosine ligase-like family, member 13

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134962.1 → NP_001128434.1  tubulin polyglutamylase TTLL13

    See identical proteins and their annotated locations for NP_001128434.1

    Status: VALIDATED

    Source sequence(s)
    BC169015
    UniProtKB/TrEMBL
    B5DFD2
    Related
    ENSRNOP00000109084.1, ENSRNOT00000136206.1
    Conserved Domains (1) summary
    pfam03133
    Location:133 → 416
    TTL; Tubulin-tyrosine ligase family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    143601777..143622344
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063262665.1 → XP_063118735.1  tubulin polyglutamylase TTLL13 isoform X1

    UniProtKB/TrEMBL
    B5DFD2

  2. XM_063262664.1 → XP_063118734.1  tubulin polyglutamylase TTLL13 isoform X1

    UniProtKB/TrEMBL
    B5DFD2

  3. XM_063262663.1 → XP_063118733.1  tubulin polyglutamylase TTLL13 isoform X1

    UniProtKB/TrEMBL
    B5DFD2

  4. XM_063262666.1 → XP_063118736.1  tubulin polyglutamylase TTLL13 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K619

  5. XM_063262670.1 → XP_063118740.1  tubulin polyglutamylase TTLL13 isoform X4

  6. XM_063262667.1 → XP_063118737.1  tubulin polyglutamylase TTLL13 isoform X3

  7. XM_063262675.1 → XP_063118745.1  tubulin polyglutamylase TTLL13 isoform X5

  8. XM_063262677.1 → XP_063118747.1  tubulin polyglutamylase TTLL13 isoform X6

  9. XM_063262678.1 → XP_063118748.1  tubulin polyglutamylase TTLL13 isoform X7

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.