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Mfsd13a major facilitator superfamily domain containing 13A [ Rattus norvegicus (Norway rat) ]

Gene ID: 309454, updated on 10-Oct-2024

Summary

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Official Symbol
Mfsd13aprovided by RGD
Official Full Name
major facilitator superfamily domain containing 13Aprovided by RGD
Primary source
RGD:1309313
See related
EnsemblRapid:ENSRNOG00000019674 AllianceGenome:RGD:1309313
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tmem180; RGD1309313
Summary
Predicted to be integral component of membrane. Orthologous to human MFSD13A (major facilitator superfamily domain containing 13A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Lung (RPKM 30.5), Adrenal (RPKM 21.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mfsd13a in Genome Data Viewer
Location:
1q54
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (255158338..255177731)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (245216610..245236314)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (266097293..266122359)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene CUE domain containing 2 Neighboring gene similar to human chromosome 10 open reading frame 95 Neighboring gene microRNA 146b Neighboring gene actin related protein 1A Neighboring gene uncharacterized LOC134484078 Neighboring gene SUFU negative regulator of hedgehog signaling

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
transmembrane protein 180

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001393812.1 → NP_001380741.1  transmembrane protein 180

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A8I5ZRA8, A6JHM3, F7EKD2
    Related
    ENSRNOP00000081136.1, ENSRNOT00000100851.2
    Conserved Domains (1) summary
    cd17481
    Location:17 → 500
    MFS_MFSD13A; Major facilitator superfamily domain containing 13A

RNA

  1. NR_172015.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    255158338..255177731
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063264998.1 → XP_063121068.1  transmembrane protein 180 isoform X1

    UniProtKB/TrEMBL
    A0A0G2JUB6
    Related
    ENSRNOP00000100244.1, ENSRNOT00000143398.1

  2. XM_017589292.3 → XP_017444781.1  transmembrane protein 180 isoform X1

    UniProtKB/TrEMBL
    A0A0G2JUB6, A0A8I5ZRA8

  3. XM_063265015.1 → XP_063121085.1  transmembrane protein 180 isoform X2

    UniProtKB/TrEMBL
    A6JHM3, F7EKD2

  4. XM_008760432.4 → XP_008758654.1  transmembrane protein 180 isoform X2

    See identical proteins and their annotated locations for XP_008758654.1

    UniProtKB/TrEMBL
    A0A8I5ZRA8, A6JHM3, F7EKD2
    Related
    ENSRNOP00000069037.3, ENSRNOT00000088243.3
    Conserved Domains (1) summary
    cd17481
    Location:17 → 500
    MFS_MFSD13A; Major facilitator superfamily domain containing 13A

  5. XM_017589293.3 → XP_017444782.2  transmembrane protein 180 isoform X3

    Conserved Domains (1) summary
    cl28910
    Location:51 → 412
    MFS; Major Facilitator Superfamily

  6. XM_063265024.1 → XP_063121094.1  transmembrane protein 180 isoform X5

  7. XM_063265030.1 → XP_063121100.1  transmembrane protein 180 isoform X6

    UniProtKB/TrEMBL
    A0A8I5Y5X5
    Related
    ENSRNOP00000077101.1, ENSRNOT00000103197.2

  8. XM_063265034.1 → XP_063121104.1  transmembrane protein 180 isoform X7

    UniProtKB/TrEMBL
    Q5XI40
    Related
    ENSRNOP00000049314.5, ENSRNOT00000043925.6

  9. XM_063265007.1 → XP_063121077.1  transmembrane protein 180 isoform X2

    UniProtKB/TrEMBL
    A6JHM3, F7EKD2
    Related
    ENSRNOP00000084701.2, ENSRNOT00000109666.2

  10. XM_063265013.1 → XP_063121083.1  transmembrane protein 180 isoform X2

    UniProtKB/TrEMBL
    A6JHM3, F7EKD2

  11. XM_063265019.1 → XP_063121089.1  transmembrane protein 180 isoform X4

Nucleotide Protein Strain
Heading Accession and Version

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