Ado 2-aminoethanethiol dioxygenase [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Adoprovided by RGD
Official Full Name: 2-aminoethanethiol dioxygenaseprovided by RGD
Primary source: RGD:1308233
See related: EnsemblRapid:ENSRNOG00000070733 AllianceGenome:RGD:1308233
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1308233
Summary: Predicted to enable cysteamine dioxygenase activity and iron ion binding activity. Predicted to be involved in cellular response to hypoxia. Predicted to be located in mitochondrion. Orthologous to human ADO (2-aminoethanethiol dioxygenase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: 20p11

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (21043694..21044862)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (21044815..21045983)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (22447996..22449176)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH139021 (e-PCR)
- UniSTS:221107

RH138042 (e-PCR)
- UniSTS:220129

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables cysteamine dioxygenase activity	ISO Inferred from Sequence Orthology more info
enables iron ion binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cellular response to hypoxia	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in mitochondrion	ISO Inferred from Sequence Orthology more info	PubMed

General protein information

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Preferred Names: 2-aminoethanethiol dioxygenase

Names: 2-aminoethanethiol (cysteamine) dioxygenase

NP_001101096.1

EC 1.13.11.19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.