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Ttc14 tetratricopeptide repeat domain 14 [ Rattus norvegicus (Norway rat) ]

Gene ID: 310314, updated on 2-Nov-2024

Summary

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Official Symbol
Ttc14provided by RGD
Official Full Name
tetratricopeptide repeat domain 14provided by RGD
Primary source
RGD:1310045
See related
EnsemblRapid:ENSRNOG00000011261 AllianceGenome:RGD:1310045
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable nucleic acid binding activity. Orthologous to human TTC14 (tetratricopeptide repeat domain 14). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 184.6), Spleen (RPKM 162.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ttc14 in Genome Data Viewer
Location:
2q24
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (118581779..118600361)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (116653543..116665072)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (120266883..120277505)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485896 Neighboring gene arginine and serine rich coiled-coil 2, pseudogene 1 Neighboring gene coiled-coil domain 39 molecular ruler complex subunit Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC108350240

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tetratricopeptide repeat protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107666.2 → NP_001101136.2  tetratricopeptide repeat protein 14

    See identical proteins and their annotated locations for NP_001101136.2

    Status: PROVISIONAL

    Source sequence(s)
    CH473961
    UniProtKB/TrEMBL
    A6IHS1, D3ZM05
    Related
    ENSRNOP00000015192.4, ENSRNOT00000015192.7
    Conserved Domains (3) summary
    smart00316
    Location:123 → 206
    S1; Ribosomal protein S1-like RNA-binding domain
    COG0457
    Location:289 → 436
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:306 → 334
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    118581779..118600361
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063281771.1 → XP_063137841.1  tetratricopeptide repeat protein 14 isoform X3

  2. XM_039102239.2 → XP_038958167.1  tetratricopeptide repeat protein 14 isoform X2

    UniProtKB/TrEMBL
    A6IHS4
    Conserved Domains (3) summary
    smart00316
    Location:123 → 206
    S1; Ribosomal protein S1-like RNA-binding domain
    COG0457
    Location:289 → 430
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:306 → 334
    TPR; TPR repeat [structural motif]

  3. XM_006232257.5 → XP_006232319.1  tetratricopeptide repeat protein 14 isoform X1

    Related
    ENSRNOP00000110367.1, ENSRNOT00000143515.1
    Conserved Domains (4) summary
    smart00316
    Location:123 → 206
    S1; Ribosomal protein S1-like RNA-binding domain
    sd00006
    Location:254 → 282
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:288 → 321
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:254 → 319
    TPR_11; TPR repeat

RNA

  1. XR_351625.4 RNA Sequence

    Related
    ENSRNOT00000156014.1
Nucleotide Protein Strain
Heading Accession and Version

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