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Entrep3 endosomal transmembrane epsin interactor 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 310640, updated on 17-Aug-2024

Summary

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Official Symbol
Entrep3provided by RGD
Official Full Name
endosomal transmembrane epsin interactor 3provided by RGD
Primary source
RGD:1306107
See related
EnsemblRapid:ENSRNOG00000020518 AllianceGenome:RGD:1306107
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam189b; RGD1306107
Summary
Predicted to enable WW domain binding activity. Predicted to be integral component of membrane. Orthologous to human FAM189B (family with sequence similarity 189 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 54.7), Spleen (RPKM 23.4) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
2q34
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176886903..176893047)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (174588984..174595281)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (188495237..188501444)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene CDC-like kinase 2 Neighboring gene microRNA 3541 Neighboring gene secretory carrier membrane protein 3 Neighboring gene uncharacterized LOC102550011 Neighboring gene glucosylceramidase beta 1 Neighboring gene transfer RNA valine (anticodon AAC) 42

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins. Ludes-Meyers JH, et al. Oncogene, 2004 Jun 24. PMID 15064722, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables WW domain binding ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein ENTREP3
Names
family with sequence similarity 189, member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107690.1 → NP_001101160.1  protein ENTREP3

    See identical proteins and their annotated locations for NP_001101160.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473976
    UniProtKB/TrEMBL
    A0A8I6ABH6, A6J6C5
    Conserved Domains (1) summary
    pfam04103
    Location:36 → 196
    CD20; CD20-like family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    176886903..176893047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039102316.2 → XP_038958244.1  protein ENTREP3 isoform X1

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:409 → 637
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 200
    CD20; CD20-like family

  2. XM_039102317.2 → XP_038958245.1  protein ENTREP3 isoform X2

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:409 → 636
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 200
    CD20; CD20-like family

  3. XM_039102322.2 → XP_038958250.1  protein ENTREP3 isoform X6

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:407 → 625
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 200
    CD20; CD20-like family

  4. XM_039102323.2 → XP_038958251.1  protein ENTREP3 isoform X7

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:395 → 623
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 200
    CD20; CD20-like family

  5. XM_008761169.4 → XP_008759391.1  protein ENTREP3 isoform X8

    UniProtKB/TrEMBL
    A0A8I6ABH6, D3Z8J6
    Conserved Domains (1) summary
    pfam04103
    Location:36 → 200
    CD20; CD20-like family

  6. XM_063281847.1 → XP_063137917.1  protein ENTREP3 isoform X16

    UniProtKB/TrEMBL
    A0A8I6ABH6

  7. XM_039102318.2 → XP_038958246.1  protein ENTREP3 isoform X3

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:408 → 636
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 200
    CD20; CD20-like family

  8. XM_039102324.2 → XP_038958252.1  protein ENTREP3 isoform X9

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:394 → 622
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 200
    CD20; CD20-like family

  9. XM_017590886.3 → XP_017446375.1  protein ENTREP3 isoform X10

    UniProtKB/TrEMBL
    A0A8I6ABH6

  10. XM_063281848.1 → XP_063137918.1  protein ENTREP3 isoform X17

    UniProtKB/TrEMBL
    A0A8I6ABH6

  11. XM_039102319.2 → XP_038958247.1  protein ENTREP3 isoform X4

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:405 → 633
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 196
    CD20; CD20-like family

  12. XM_063281845.1 → XP_063137915.1  protein ENTREP3 isoform X12

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Related
    ENSRNOP00000027828.8, ENSRNOT00000027828.9

  13. XM_006232664.4 → XP_006232726.1  protein ENTREP3 isoform X11

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (1) summary
    pfam04103
    Location:36 → 196
    CD20; CD20-like family

  14. XM_063281849.1 → XP_063137919.1  protein ENTREP3 isoform X18

    UniProtKB/TrEMBL
    A0A8I6ABH6

  15. XM_039102320.2 → XP_038958248.1  protein ENTREP3 isoform X5

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:404 → 632
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 196
    CD20; CD20-like family

  16. XM_063281846.1 → XP_063137916.1  protein ENTREP3 isoform X14

    UniProtKB/TrEMBL
    A0A8I6ABH6

  17. XM_063281851.1 → XP_063137921.1  protein ENTREP3 isoform X19

    UniProtKB/TrEMBL
    A0A8I6ABH6

  18. XM_039102328.2 → XP_038958256.1  protein ENTREP3 isoform X23

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:365 → 593
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 156
    CD20; CD20-like family

  19. XM_063281855.1 → XP_063137925.1  protein ENTREP3 isoform X26

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Related
    ENSRNOP00000104427.1, ENSRNOT00000166647.1

  20. XM_063281856.1 → XP_063137926.1  protein ENTREP3 isoform X28

    UniProtKB/TrEMBL
    A0A8I6ABH6

  21. XM_039102329.2 → XP_038958257.1  protein ENTREP3 isoform X24

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:364 → 592
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 156
    CD20; CD20-like family

  22. XM_039102325.2 → XP_038958253.1  protein ENTREP3 isoform X13

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:390 → 618
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 181
    CD20; CD20-like family

  23. XM_039102326.2 → XP_038958254.1  protein ENTREP3 isoform X15

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:386 → 614
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 177
    CD20; CD20-like family

  24. XM_063281852.1 → XP_063137922.1  protein ENTREP3 isoform X20

    UniProtKB/TrEMBL
    A0A8I6ABH6

  25. XM_039102327.2 → XP_038958255.1  protein ENTREP3 isoform X21

    UniProtKB/TrEMBL
    A0A8I6ABH6, A0A8I6GFC2
    Related
    ENSRNOP00000086795.2, ENSRNOT00000110005.2
    Conserved Domains (2) summary
    PHA03247
    Location:372 → 599
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 177
    CD20; CD20-like family

  26. XM_063281853.1 → XP_063137923.1  protein ENTREP3 isoform X22

    UniProtKB/TrEMBL
    A0A8I6ABH6

  27. XM_063281854.1 → XP_063137924.1  protein ENTREP3 isoform X25

    UniProtKB/TrEMBL
    A0A8I6ABH6

  28. XM_039102330.2 → XP_038958258.1  protein ENTREP3 isoform X27

    UniProtKB/TrEMBL
    A0A8I6ABH6
    Conserved Domains (2) summary
    PHA03247
    Location:346 → 574
    PHA03247; large tegument protein UL36; Provisional
    pfam04103
    Location:36 → 137
    CD20; CD20-like family

  29. XM_063281857.1 → XP_063137927.1  protein ENTREP3 isoform X29

    UniProtKB/TrEMBL
    A0A8I6ABH6

  30. XM_063281858.1 → XP_063137928.1  protein ENTREP3 isoform X30

    UniProtKB/TrEMBL
    A0A8I6ABH6

  31. XM_039102332.2 → XP_038958260.1  protein ENTREP3 isoform X31

    Conserved Domains (1) summary
    PRK12323
    Location:231 → 446
    PRK12323; DNA polymerase III subunit gamma/tau

  32. XM_063281859.1 → XP_063137929.1  protein ENTREP3 isoform X31

  33. XM_063281861.1 → XP_063137931.1  protein ENTREP3 isoform X33

  34. XM_063281862.1 → XP_063137932.1  protein ENTREP3 isoform X34

  35. XM_063281860.1 → XP_063137930.1  protein ENTREP3 isoform X32

Nucleotide Protein Strain
Heading Accession and Version

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