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Golph3l golgi phosphoprotein 3-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 310669, updated on 2-Nov-2024

Summary

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Official Symbol
Golph3lprovided by RGD
Official Full Name
golgi phosphoprotein 3-likeprovided by RGD
Primary source
RGD:1359281
See related
EnsemblRapid:ENSRNOG00000047620 AllianceGenome:RGD:1359281
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable cargo adaptor activity and phosphatidylinositol-4-phosphate binding activity. Predicted to be involved in several processes, including Golgi vesicle transport; positive regulation of protein secretion; and protein targeting to Golgi apparatus. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi cisterna; cytosol; and trans-Golgi network. Orthologous to human GOLPH3L (golgi phosphoprotein 3 like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 104.9), Thymus (RPKM 103.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Golph3l in Genome Data Viewer
Location:
2q34
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (185840879..185872037)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (183151941..183183094)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (197720259..197749060)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene cathepsin S Neighboring gene HORMA domain containing 1 Neighboring gene transfer RNA leucine (anticodon AAG) 16 Neighboring gene RNA, U6 small nuclear 857 Neighboring gene endosulfine alpha Neighboring gene MCL1 apoptosis regulator, BCL2 family member

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. GOLPH3L antagonizes GOLPH3 to determine Golgi morphology. Ng MM, et al. Mol Biol Cell, 2013 Mar. PMID 23345592, Free PMC Article
  2. Proteomics characterization of abundant Golgi membrane proteins. Bell AW, et al. J Biol Chem, 2001 Feb 16. PMID 11042173
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC94181

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cargo adaptor activity IEA
Inferred from Electronic Annotation
more info
  
enables cargo adaptor activity ISO
Inferred from Sequence Orthology
more info
  
enables phosphatidylinositol-4-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol-4-phosphate binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylinositol-4-phosphate binding ISO
Inferred from Sequence Orthology
more info
  
enables phosphatidylinositol-4-phosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Golgi organization IEA
Inferred from Electronic Annotation
more info
  
involved_in Golgi organization ISO
Inferred from Sequence Orthology
more info
  
involved_in Golgi organization ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in Golgi to plasma membrane protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Golgi vesicle budding IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of protein secretion IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of protein secretion ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of protein secretion ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein targeting to Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
involved_in protein targeting to Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
is_active_in Golgi cisterna IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi cisterna ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in trans-Golgi network ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
Golgi phosphoprotein 3-like
Names
GPP34-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007698.1 → NP_001007699.1  Golgi phosphoprotein 3-like

    See identical proteins and their annotated locations for NP_001007699.1

    Status: PROVISIONAL

    Source sequence(s)
    BC081987
    UniProtKB/Swiss-Prot
    Q66H74
    UniProtKB/TrEMBL
    A0A0G2K9Q1, A6K300
    Related
    ENSRNOP00000064938.1, ENSRNOT00000070919.4
    Conserved Domains (1) summary
    pfam05719
    Location:48 → 259
    GPP34; Golgi phosphoprotein 3 (GPP34)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    185840879..185872037
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039102357.2 → XP_038958285.1  Golgi phosphoprotein 3-like isoform X1

    UniProtKB/TrEMBL
    A0A0G2K9Q1
    Related
    ENSRNOP00000106584.1, ENSRNOT00000165904.1
    Conserved Domains (1) summary
    pfam05719
    Location:56 → 267
    GPP34; Golgi phosphoprotein 3 (GPP34)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q66H74.1 GenPept UniProtKB/Swiss-Prot:Q66H74

Gene LinkOut

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