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Cttnbp2nl CTTNBP2 N-terminal like [ Rattus norvegicus (Norway rat) ]

Gene ID: 310760, updated on 2-Nov-2024

Summary

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Official Symbol
Cttnbp2nlprovided by RGD
Official Full Name
CTTNBP2 N-terminal likeprovided by RGD
Primary source
RGD:1310822
See related
EnsemblRapid:ENSRNOG00000014479 AllianceGenome:RGD:1310822
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310822
Summary
Predicted to enable protein phosphatase 2A binding activity. Predicted to be involved in protein localization to actin cytoskeleton. Predicted to act upstream of or within negative regulation of transmembrane transport; negative regulation of transporter activity; and protein dephosphorylation. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in actin cytoskeleton. Orthologous to human CTTNBP2NL (CTTNBP2 N-terminal like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 153.6), Kidney (RPKM 103.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Cttnbp2nl in Genome Data Viewer
Location:
2q34
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (195196318..195244792, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (192507963..192554548, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (207495056..207541808, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene Wnt family member 2B Neighboring gene small ribosomal subunit protein eS6-like Neighboring gene uncharacterized LOC134485665 Neighboring gene uncharacterized LOC102548297 Neighboring gene ribosomal protein S23, pseudogene 7 Neighboring gene uncharacterized LOC102548357

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Genetic variants related to gap junctions and hormone secretion influence conception rates in cows. Sugimoto M, et al. Proc Natl Acad Sci U S A, 2013 Nov 26. PMID 24218568, Free PMC Article
  2. Identification and analysis of plasticity-induced late-response genes. Hong SJ, et al. Proc Natl Acad Sci U S A, 2004 Feb 17. PMID 14766980, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein phosphatase 2A binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of transporter activity IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of transporter activity ISO
Inferred from Sequence Orthology
more info
  
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein dephosphorylation ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of FAR/SIN/STRIPAK complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
CTTNBP2 N-terminal-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107712.2 → NP_001101182.2  CTTNBP2 N-terminal-like protein

    See identical proteins and their annotated locations for NP_001101182.2

    Status: VALIDATED

    Source sequence(s)
    CB724536, JAXUCZ010000002
    UniProtKB/TrEMBL
    A6K3Q4, A6K3Q5, D4A8X8
    Related
    ENSRNOP00000019680.4, ENSRNOT00000019680.7
    Conserved Domains (2) summary
    TIGR02168
    Location:100 → 287
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam09727
    Location:5 → 188
    CortBP2; Cortactin-binding protein-2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    195196318..195244792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063281915.1 → XP_063137985.1  CTTNBP2 N-terminal-like protein isoform X1

    UniProtKB/TrEMBL
    A6K3Q5, D4A8X8

  2. XM_063281913.1 → XP_063137983.1  CTTNBP2 N-terminal-like protein isoform X1

    UniProtKB/TrEMBL
    A6K3Q5, D4A8X8

  3. XM_063281914.1 → XP_063137984.1  CTTNBP2 N-terminal-like protein isoform X1

    UniProtKB/TrEMBL
    A6K3Q5, D4A8X8
Nucleotide Protein Strain
Heading Accession and Version

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