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Wdr47 WD repeat domain 47 [ Rattus norvegicus (Norway rat) ]

Gene ID: 310785, updated on 10-Jul-2024

Summary

Official Symbol
Wdr47provided by RGD
Official Full Name
WD repeat domain 47provided by RGD
Primary source
RGD:1309181
See related
EnsemblRapid:ENSRNOG00000020330 AllianceGenome:RGD:1309181
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309181
Summary
Located in cytoplasm. Orthologous to human WDR47 (WD repeat domain 47). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 257.3), Testes (RPKM 79.2) and 9 other tissues See more
Orthologs
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Genomic context

See Wdr47 in Genome Data Viewer
Location:
2q34
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (198914977..198975844)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (196226757..196287739)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (211380894..211441817)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 167B Neighboring gene TATA-box binding protein associated factor 13 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene chloride channel CLIC-like 1 Neighboring gene G-protein signaling modulator 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within adult locomotory behavior ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within anterior commissure morphogenesis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within autophagy ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within brain development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cerebral cortex development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cerebral cortex radial glia-guided migration ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within corpus callosum development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within detection of hot stimulus involved in thermoception ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within locomotory behavior ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within microtubule cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within motor behavior ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of microtubule depolymerization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within neural precursor cell proliferation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within neuron projection development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within neuronal stem cell population maintenance ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in axon ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in growth cone ISO
Inferred from Sequence Orthology
more info
 
located_in microtubule ISO
Inferred from Sequence Orthology
more info
 
located_in neuron projection ISO
Inferred from Sequence Orthology
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
WD repeat-containing protein 47

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100702.1NP_001094172.1  WD repeat-containing protein 47

    See identical proteins and their annotated locations for NP_001094172.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473952
    UniProtKB/TrEMBL
    A0A8I5Y1M2, A6HV14, G3V9M3
    Conserved Domains (5) summary
    smart00667
    Location:942
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45102
    CTLH; C-terminal to LisH motif
    COG2319
    Location:547920
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:601917
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:613661
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    198914977..198975844
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006233155.5XP_006233217.1  WD repeat-containing protein 47 isoform X5

    See identical proteins and their annotated locations for XP_006233217.1

    UniProtKB/TrEMBL
    A0A8I5Y1M2
    Related
    ENSRNOP00000052715.3, ENSRNOT00000055862.4
    Conserved Domains (5) summary
    smart00667
    Location:942
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45102
    CTLH; C-terminal to LisH motif
    COG2319
    Location:554927
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:608924
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:620668
    7WD40; WD40 repeat [structural motif]
  2. XM_063281931.1XP_063138001.1  WD repeat-containing protein 47 isoform X8

    UniProtKB/TrEMBL
    A0A8I5Y1M2
  3. XM_063281928.1XP_063137998.1  WD repeat-containing protein 47 isoform X5

    UniProtKB/TrEMBL
    A0A8I5Y1M2
  4. XM_063281924.1XP_063137994.1  WD repeat-containing protein 47 isoform X2

    UniProtKB/TrEMBL
    A0A8I5Y1M2
  5. XM_063281923.1XP_063137993.1  WD repeat-containing protein 47 isoform X1

    UniProtKB/TrEMBL
    A0A8I5Y1M2
  6. XM_063281926.1XP_063137996.1  WD repeat-containing protein 47 isoform X4

    UniProtKB/TrEMBL
    A0A8I5Y1M2
  7. XM_063281925.1XP_063137995.1  WD repeat-containing protein 47 isoform X3

    UniProtKB/TrEMBL
    A0A8I5Y1M2
  8. XM_063281927.1XP_063137997.1  WD repeat-containing protein 47 isoform X5

    UniProtKB/TrEMBL
    A0A8I5Y1M2
  9. XM_063281929.1XP_063137999.1  WD repeat-containing protein 47 isoform X6

    UniProtKB/TrEMBL
    A0A8I5Y1M2, A6HV14, G3V9M3
    Related
    ENSRNOP00000077485.2, ENSRNOT00000105849.2
  10. XM_063281930.1XP_063138000.1  WD repeat-containing protein 47 isoform X7

    UniProtKB/TrEMBL
    A0A8I5Y1M2