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Cytip cytohesin 1 interacting protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 311047, updated on 2-Nov-2024

Summary

Official Symbol
Cytipprovided by RGD
Official Full Name
cytohesin 1 interacting proteinprovided by RGD
Primary source
RGD:1307990
See related
EnsemblRapid:ENSRNOG00000004772 AllianceGenome:RGD:1307990
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Pscdbp
Summary
Predicted to be involved in regulation of cell adhesion. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cell cortex. Orthologous to human CYTIP (cytohesin 1 interacting protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 469.7), Thymus (RPKM 436.6) and 4 other tissues See more
Orthologs
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Genomic context

See Cytip in Genome Data Viewer
Location:
3q21
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (63106895..63183769, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (42698058..42774955, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (44150494..44225723, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 5 Neighboring gene ermin Neighboring gene uncharacterized LOC102555754 Neighboring gene activin A receptor type 1C Neighboring gene uncharacterized LOC134486284

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in regulation of cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of cell adhesion ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cell cortex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in early endosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cytohesin-interacting protein
Names
pleckstrin homology Sec7 and coiled-coil domain-binding protein
pleckstrin homology, Sec7 and coiled-coil domains, binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012086.1NP_001012086.1  cytohesin-interacting protein

    See identical proteins and their annotated locations for NP_001012086.1

    Status: PROVISIONAL

    Source sequence(s)
    BC088207
    UniProtKB/Swiss-Prot
    Q5I0L6
    UniProtKB/TrEMBL
    A6JF54
    Related
    ENSRNOP00000006387.4, ENSRNOT00000006387.7
    Conserved Domains (1) summary
    cd00992
    Location:76161
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    63106895..63183769 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006234202.5XP_006234264.1  cytohesin-interacting protein isoform X1

    UniProtKB/TrEMBL
    A6JF54
    Conserved Domains (1) summary
    cd00992
    Location:30115
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  2. XM_039104820.2XP_038960748.1  cytohesin-interacting protein isoform X2

    Conserved Domains (1) summary
    cd00992
    Location:252
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...