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Itprid2 ITPR interacting domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 311146, updated on 10-Jul-2024

Summary

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Official Symbol
Itprid2provided by RGD
Official Full Name
ITPR interacting domain containing 2provided by RGD
Primary source
RGD:1310767
See related
EnsemblRapid:ENSRNOG00000005865 AllianceGenome:RGD:1310767
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ssfa2
Summary
Predicted to enable actin filament binding activity. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Orthologous to human ITPRID2 (ITPR interacting domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 216.3), Thymus (RPKM 146.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Itprid2 in Genome Data Viewer
Location:
3q24
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (84943572..84980993)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (64536707..64573978)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (66593767..66631143)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102553121 Neighboring gene uncharacterized LOC103691830 Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 1C Neighboring gene phosphodiesterase 1A Neighboring gene uncharacterized LOC134486399

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Deregulated expression of KRAP, a novel gene encoding actin-interacting protein, in human colon cancer cells. Inokuchi J, et al. J Hum Genet, 2004. PMID 14673706

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables actin filament binding ISO
Inferred from Sequence Orthology
more info
  
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein ITPRID2
Names
sperm specific antigen 2
sperm-specific antigen 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107738.1 → NP_001101208.1  protein ITPRID2

    See identical proteins and their annotated locations for NP_001101208.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473949
    UniProtKB/TrEMBL
    A0A8I5ZTD5, A6HML6, D3ZLC3
    Related
    ENSRNOP00000008046.5, ENSRNOT00000008046.8
    Conserved Domains (2) summary
    pfam14722
    Location:146 → 297
    KRAP_IP3R_bind; Ki-ras-induced actin-interacting protein-IP3R-interacting domain
    pfam14723
    Location:865 → 1032
    SSFA2_C; Sperm-specific antigen 2 C-terminus

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    84943572..84980993
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017591707.3 → XP_017447196.1  protein ITPRID2 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZTD5

  2. XM_039104867.2 → XP_038960795.1  protein ITPRID2 isoform X3

    Conserved Domains (2) summary
    pfam14722
    Location:146 → 297
    KRAP_IP3R_bind; Ki-ras-induced actin-interacting protein-IP3R-interacting domain
    pfam14723
    Location:863 → 930
    SSFA2_C; Sperm-specific antigen 2 C-terminus

  3. XM_063283643.1 → XP_063139713.1  protein ITPRID2 isoform X2

    UniProtKB/TrEMBL
    A0A8I6A5N9
    Related
    ENSRNOP00000086622.1, ENSRNOT00000105305.2
Nucleotide Protein Strain
Heading Accession and Version

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