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Rpusd2 RNA pseudouridine synthase domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 311326, updated on 2-Nov-2024

Summary

Symbol
Rpusd2provided by RGD
Full Name
RNA pseudouridine synthase domain containing 2provided by RGD
Primary source
RGD:1306147
See related
EnsemblRapid:ENSRNOG00000010528 AllianceGenome:RGD:1306147
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306147
Summary
Predicted to enable pseudouridine synthase activity. Predicted to be involved in enzyme-directed rRNA pseudouridine synthesis and mRNA pseudouridine synthesis. Orthologous to human RPUSD2 (RNA pseudouridine synthase domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 39.3), Thymus (RPKM 36.8) and 9 other tissues See more
Orthologs
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Genomic context

See Rpusd2 in Genome Data Viewer
Location:
3q35
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (126471620..126476869)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (106017759..106023010)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (110835654..110840903)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486301 Neighboring gene coiled-coil domain containing 32 Neighboring gene transfer RNA serine (anticodon GCU) 4 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene kinetochore scaffold 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables pseudouridine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables pseudouridine synthase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in enzyme-directed rRNA pseudouridine synthesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mRNA pseudouridine synthesis ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
pseudouridylate synthase RPUSD2
Names
CG6187-like
RNA pseudouridylate synthase domain containing 2
RNA pseudouridylate synthase domain-containing protein 2
RNA pseudouridylate synthase domain-containing protein 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135845.1NP_001129317.1  pseudouridylate synthase RPUSD2

    See identical proteins and their annotated locations for NP_001129317.1

    Status: INFERRED

    Source sequence(s)
    CH473949
    UniProtKB/TrEMBL
    A6HPD8, D4ACD4
    Related
    ENSRNOP00000014129.6, ENSRNOT00000014129.7
    Conserved Domains (1) summary
    cd02557
    Location:221404
    PseudoU_synth_ScRIB2; Pseudouridine synthases similar to Saccharomyces cerevisiae RIB2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    126471620..126476869
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)