Zmynd19 zinc finger, MYND-type containing 19 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Zmynd19provided by RGD
Full Name: zinc finger, MYND-type containing 19provided by RGD
Primary source: RGD:735079
See related: EnsemblRapid:ENSRNOG00000007752 AllianceGenome:RGD:735079
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: mizip
Summary: Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm; membrane; and synapse. Orthologous to human ZMYND19 (zinc finger MYND-type containing 19). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Testes (RPKM 87.4), Thymus (RPKM 82.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3p13

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (28156314..28167903)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (7758133..7769722)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (2158995..2168873)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

data support the notion that MIZIP might interact with melanin-concentrating hormone receptor 1 (MCHR1) in a cell type specific manner in vivo, suggesting a role in the regulation of MCH signalling in distinct regions of the mammalian brain
Title: Immunohistochemical distribution of MIZIP and its co-expression with the Melanin-concentrating hormone receptor 1 in the adult rodent brain.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
is_active_in synapse	IBA Inferred from Biological aspect of Ancestor more info
located_in synapse	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: zinc finger MYND domain-containing protein 19

Names: MCH-R1-interacting zinc finger protein; melanin-concentrating hormone receptor 1 interacting zinc-finger protein; zinc finger MYND domain-containing protein 19-like; zinc finger, MYND domain containing 19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198770.3 → NP_942065.1 zinc finger MYND domain-containing protein 19

See identical proteins and their annotated locations for NP_942065.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/Swiss-Prot

Q7TSV3

UniProtKB/TrEMBL

A0A8I6AB25, A6JSZ6

Related

ENSRNOP00000010270.5, ENSRNOT00000010270.9

Conserved Domains (2) summary

pfam01753
Location:174 → 212

zf-MYND; MYND finger

cl00083
Location:66 → 105

HNHc; HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086021.1 Reference GRCr8

Range

28156314..28167903

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063283922.1 → XP_063139992.1 zinc finger MYND domain-containing protein 19 isoform X1

UniProtKB/TrEMBL

A0A8I6AB25
XM_063283921.1 → XP_063139991.1 zinc finger MYND domain-containing protein 19 isoform X1

UniProtKB/TrEMBL

A0A8I6AB25