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Osgin2 oxidative stress induced growth inhibitor family member 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 313085, updated on 2-Nov-2024

Summary

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Official Symbol
Osgin2provided by RGD
Official Full Name
oxidative stress induced growth inhibitor family member 2provided by RGD
Primary source
RGD:1306323
See related
EnsemblRapid:ENSRNOG00000009358 AllianceGenome:RGD:1306323
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306323
Summary
Predicted to enable growth factor activity. Predicted to be involved in negative regulation of cell growth. Orthologous to human OSGIN2 (oxidative stress induced growth inhibitor family member 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Muscle (RPKM 101.7), Heart (RPKM 57.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Osgin2 in Genome Data Viewer
Location:
5q13
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (34297417..34316353, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (29500406..29519340, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (29663131..29683634, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L30, pseudogene 6 Neighboring gene nibrin Neighboring gene tubulin, alpha 2 like, pseudogene 1 Neighboring gene GA binding protein transcription factor subunit beta 2, pseudogene 1 Neighboring gene receptor-interacting serine-threonine kinase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables growth factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of cell growth IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
oxidative stress-induced growth inhibitor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399569.1 → NP_001386498.1  oxidative stress-induced growth inhibitor 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A6IIB1, D3ZB49
    Related
    ENSRNOP00000012394.4, ENSRNOT00000012394.8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    34297417..34316353 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006237919.5 → XP_006237981.1  oxidative stress-induced growth inhibitor 2 isoform X1

    See identical proteins and their annotated locations for XP_006237981.1

    UniProtKB/TrEMBL
    A0A8I6ASB1, A6IIB2
    Conserved Domains (1) summary
    PRK12770
    Location:258 → 333
    PRK12770; putative glutamate synthase subunit beta; Provisional

  2. XM_063287579.1 → XP_063143649.1  oxidative stress-induced growth inhibitor 2 isoform X2

    Related
    ENSRNOP00000092835.2, ENSRNOT00000095460.2

  3. XM_039110948.1 → XP_038966876.1  oxidative stress-induced growth inhibitor 2 isoform X3

    UniProtKB/TrEMBL
    A6IIB3
    Conserved Domains (1) summary
    PRK12770
    Location:125 → 200
    PRK12770; putative glutamate synthase subunit beta; Provisional

  4. XM_063287580.1 → XP_063143650.1  oxidative stress-induced growth inhibitor 2 isoform X4

    UniProtKB/TrEMBL
    A0A8I6GKD4

  5. XM_039110950.2 → XP_038966878.1  oxidative stress-induced growth inhibitor 2 isoform X5

Nucleotide Protein Strain
Heading Accession and Version

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