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Slc7a13 solute carrier family 7 member 13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 313089, updated on 2-Nov-2024

Summary

Official Symbol
Slc7a13provided by RGD
Official Full Name
solute carrier family 7 member 13provided by RGD
Primary source
RGD:1311633
See related
EnsemblRapid:ENSRNOG00000024903 AllianceGenome:RGD:1311633
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable L-amino acid transmembrane transporter activity and protein heterodimerization activity. Predicted to be involved in L-cystine transport; L-glutamate transmembrane transport; and aspartate transmembrane transport. Predicted to be active in apical plasma membrane. Orthologous to human SLC7A13 (solute carrier family 7 member 13). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 6978.7) See more
Orthologs
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Genomic context

See Slc7a13 in Genome Data Viewer
Location:
5q13
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (38074171..38096856)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (33277400..33298186)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (33784757..33805446)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene WW domain containing E3 ubiquitin protein ligase 1 Neighboring gene uncharacterized LOC134478942 Neighboring gene 60S ribosomal protein L13 pseudogene Neighboring gene ATPase H+ transporting V0 subunit D2 Neighboring gene alpha tocopherol transfer protein

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
 
enables protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in L-cystine transport ISO
Inferred from Sequence Orthology
more info
 
involved_in L-glutamate transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in aspartate transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
solute carrier family 7 member 13
Names
sodium-independent aspartate/glutamate transporter 1
solute carrier family 7 (anionic amino acid transporter), member 13
solute carrier family 7, (cationic amino acid transporter, y+ system) member 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012100.2NP_001012100.1  solute carrier family 7 member 13

    See identical proteins and their annotated locations for NP_001012100.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/Swiss-Prot
    Q5RKI7
    UniProtKB/TrEMBL
    A6IID1
    Related
    ENSRNOP00000032751.4, ENSRNOT00000035685.8
    Conserved Domains (1) summary
    COG0531
    Location:11454
    PotE; Amino acid transporter [Amino acid transport and metabolism]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    38074171..38096856
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063287581.1XP_063143651.1  solute carrier family 7 member 13 isoform X1