U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Lad1 ladinin 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 313325, updated on 17-Aug-2024

Summary

Official Symbol
Lad1provided by RGD
Official Full Name
ladinin 1provided by RGD
Primary source
RGD:1310652
See related
EnsemblRapid:ENSRNOG00000009144 AllianceGenome:RGD:1310652
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable structural molecule activity. Predicted to be located in actin cytoskeleton. Orthologous to human LAD1 (ladinin 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 147.8), Lung (RPKM 32.8) and 4 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Lad1 in Genome Data Viewer
Location:
13q13
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (49801347..49815709)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (47249605..47263967)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (52645257..52659619)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481563 Neighboring gene troponin I1, slow skeletal type Neighboring gene troponin T2, cardiac type Neighboring gene plakophilin 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107942.2NP_001101412.2  ladinin-1

    See identical proteins and their annotated locations for NP_001101412.2

    Status: VALIDATED

    Source sequence(s)
    BC167044, BP504151, JAXUCZ010000013
    UniProtKB/TrEMBL
    A0A8I5ZPS3, A6ICG6, G3V779
    Related
    ENSRNOP00000091877.2, ENSRNOT00000100192.2
    Conserved Domains (1) summary
    pfam02029
    Location:367507
    Caldesmon; Caldesmon

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    49801347..49815709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)