U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Focad focadhesin [ Rattus norvegicus (Norway rat) ]

Gene ID: 313346, updated on 10-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
Focadprovided by RGD
Official Full Name
focadhesinprovided by RGD
Primary source
RGD:1311849
See related
EnsemblRapid:ENSRNOG00000024402 AllianceGenome:RGD:1311849
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ir22; RGD1311849
Summary
Predicted to be located in focal adhesion. Orthologous to human FOCAD (focadhesin). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 101.0), Muscle (RPKM 96.0) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Focad in Genome Data Viewer
Location:
5q32
Exon count:
48
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (107610489..107932485)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (102564560..102886587)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (106409411..106729308)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108350995 Neighboring gene MLLT3, super elongation complex subunit Neighboring gene small nucleolar RNA SNORA17 Neighboring gene 3-hydroxyacyl-CoA dehydratase 4 Neighboring gene interferon beta 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Identification of transcriptionally regulated genes in response to cellular iron availability in rat hippocampus. Liu M, et al. Mol Cell Biochem, 2007 Jun. PMID 17186380
  2. KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas. Brockschmidt A, et al. Brain, 2012 Apr. PMID 22427331

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in regulation of post-transcriptional gene silencing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in focal adhesion ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
focadhesin

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427695.1 → NP_001414624.1  focadhesin

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    F1LU27
    Related
    ENSRNOP00000055189.3, ENSRNOT00000058387.6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    107610489..107932485
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039111093.2 → XP_038967021.1  focadhesin isoform X1

    UniProtKB/TrEMBL
    A0A8I6AQM8
    Related
    ENSRNOP00000104359.1, ENSRNOT00000173561.1
    Conserved Domains (2) summary
    pfam11229
    Location:1113 → 1701
    Focadhesin
    pfam12530
    Location:393 → 617
    DUF3730; Protein of unknown function (DUF3730)

  2. XM_017593754.3 → XP_017449243.1  focadhesin isoform X1

    UniProtKB/TrEMBL
    A0A8I6AQM8
    Conserved Domains (2) summary
    pfam11229
    Location:1113 → 1701
    Focadhesin
    pfam12530
    Location:393 → 617
    DUF3730; Protein of unknown function (DUF3730)

  3. XM_063287636.1 → XP_063143706.1  focadhesin isoform X2

  4. XM_039111095.2 → XP_038967023.1  focadhesin isoform X3

    Conserved Domains (2) summary
    pfam11229
    Location:717 → 1305
    Focadhesin
    pfam12530
    Location:1 → 221
    DUF3730; Protein of unknown function (DUF3730)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.