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Fdx2 ferredoxin 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 313786, updated on 19-Sep-2024

Summary

Official Symbol
Fdx2provided by RGD
Official Full Name
ferredoxin 2provided by RGD
Primary source
RGD:1561264
See related
EnsemblRapid:ENSRNOG00000023020 AllianceGenome:RGD:1561264
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fdx1l; RGD1561264
Summary
Predicted to enable 2 iron, 2 sulfur cluster binding activity and electron transfer activity. Predicted to be involved in electron transport chain. Human ortholog(s) of this gene implicated in mitochondrial myopathy. Orthologous to human FDX2 (ferredoxin 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 123.1), Brain (RPKM 120.4) and 9 other tissues See more
Orthologs
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Genomic context

See Fdx2 in Genome Data Viewer
Location:
8q13
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (27881091..27886230, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (19604916..19609832, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (22086534..22091450, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene intercellular adhesion molecule 5 Neighboring gene zinc finger, GATA-like protein 1 Neighboring gene ribonucleoprotein, PTB-binding 1 Neighboring gene tyrosine kinase 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables 2 iron, 2 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables electron transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables electron transfer activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in P450-containing electron transport chain IEA
Inferred from Electronic Annotation
more info
 
involved_in [2Fe-2S] cluster assembly ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of [4Fe-4S] cluster assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in electron transport chain IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
ferredoxin-2, mitochondrial
Names
adrenodoxin-like protein, mitochondrial
ferredoxin 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108002.1NP_001101472.1  ferredoxin-2, mitochondrial

    See identical proteins and their annotated locations for NP_001101472.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473993
    UniProtKB/TrEMBL
    A6JNN6, D4A8N2
    Related
    ENSRNOP00000028127.4, ENSRNOT00000028127.7
    Conserved Domains (1) summary
    PLN02593
    Location:59174
    PLN02593; adrenodoxin-like ferredoxin protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    27881091..27886230 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_010053956.1 RNA Sequence