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Ankmy2 ankyrin repeat and MYND domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314046, updated on 10-Jul-2024

Summary

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Official Symbol
Ankmy2provided by RGD
Official Full Name
ankyrin repeat and MYND domain containing 2provided by RGD
Primary source
RGD:1306017
See related
EnsemblRapid:ENSRNOG00000005623 AllianceGenome:RGD:1306017
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable enzyme binding activity. Orthologous to human ANKMY2 (ankyrin repeat and MYND domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 161.5), Spleen (RPKM 120.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ankmy2 in Genome Data Viewer
Location:
6q16
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (58616251..58657634)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (52888959..52930343)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (55646905..55689223)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479367 Neighboring gene basic leucine zipper and W2 domains 2 Neighboring gene non-POU domain containing, octamer-binding, pseudogene 3 Neighboring gene leucine rich repeat containing 72 Neighboring gene MYC associated factor X, pseudogene 2 Neighboring gene ribosomal protein S26, pseudogene 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Localization of a guanylyl cyclase to chemosensory cilia requires the novel ciliary MYND domain protein DAF-25. Jensen VL, et al. PLoS Genet, 2010 Nov 24. PMID 21124868, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cilium IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ankyrin repeat and MYND domain-containing protein 2
Names
guanine nucleotide binding protein, alpha 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108019.1 → NP_001101489.1  ankyrin repeat and MYND domain-containing protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001101489.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473947
    UniProtKB/TrEMBL
    A6HBB0, D3ZC34
    Related
    ENSRNOP00000062801.1, ENSRNOT00000064822.4
    Conserved Domains (4) summary
    cd00204
    Location:31 → 132
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam01753
    Location:295 → 314
    zf-MYND; MYND finger
    pfam13857
    Location:31 → 87
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:16 → 43
    ANK; ANK repeat [structural motif]

  2. NM_001399649.1 → NP_001386578.1  ankyrin repeat and MYND domain-containing protein 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A0G2K8N6
    Related
    ENSRNOP00000074676.1, ENSRNOT00000091488.3

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    58616251..58657634
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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