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Unc79 unc-79 homolog, NALCN channel complex subunit [ Rattus norvegicus (Norway rat) ]

Gene ID: 314401, updated on 17-Aug-2024

Summary

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Symbol
Unc79provided by RGD
Full Name
unc-79 homolog, NALCN channel complex subunitprovided by RGD
Primary source
RGD:1311117
See related
EnsemblRapid:ENSRNOG00000008728 AllianceGenome:RGD:1311117
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311117
Summary
Predicted to act upstream of or within behavioral response to ethanol. Orthologous to human UNC79 (unc-79 homolog, NALCN channel complex subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 66.0), Spleen (RPKM 18.1) and 4 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
6q32
Exon count:
56
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (127841671..128092380)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (122082369..122327641)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (126818580..127069026)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene nuclear nucleic acid-binding protein C1D-like Neighboring gene BTB domain containing 7 Neighboring gene cytochrome c oxidase subunit 8C Neighboring gene enolase 1 like 1 Neighboring gene proline rich membrane anchor 1 Neighboring gene uncharacterized LOC120103607 Neighboring gene family with sequence similarity 181, member A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A long noncoding RNA LOC103690121 promotes hippocampus neuronal apoptosis in streptozotocin-induced type 1 diabetes. Hao L, et al. Neurosci Lett, 2019 Jun 11. PMID 30851305
  2. Conserved role of unc-79 in ethanol responses in lightweight mutant mice. Speca DJ, et al. PLoS Genet, 2010 Aug 12. PMID 20714347, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. lncRNA LOC103690121 promoted STZ-induced cognitive impairment in diabetic rats by promoting neuron apoptosis through PI3K/Akt signaling pathway
    Title: A long noncoding RNA LOC103690121 promotes hippocampus neuronal apoptosis in streptozotocin-induced type 1 diabetes.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within adult behavior ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within behavioral response to ethanol ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within multicellular organism growth ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within suckling behavior ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein unc-79 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271253.2 → NP_001258182.1  protein unc-79 homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A8I5ZJJ4
    Conserved Domains (1) summary
    pfam14776
    Location:1 → 468
    UNC-79; Cation-channel complex subunit UNC-79

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    127841671..128092380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063261997.1 → XP_063118067.1  protein unc-79 homolog isoform X22

    UniProtKB/TrEMBL
    D3ZSV8

  2. XM_063261998.1 → XP_063118068.1  protein unc-79 homolog isoform X23

    UniProtKB/TrEMBL
    D3ZSV8

  3. XM_063261995.1 → XP_063118065.1  protein unc-79 homolog isoform X21

    UniProtKB/TrEMBL
    A0A8I5ZJJ4

  4. XM_063261992.1 → XP_063118062.1  protein unc-79 homolog isoform X18

    UniProtKB/TrEMBL
    A0A8I6AJ87, D3ZSV8

  5. XM_063261990.1 → XP_063118060.1  protein unc-79 homolog isoform X16

    UniProtKB/TrEMBL
    D3ZSV8

  6. XM_063261980.1 → XP_063118050.1  protein unc-79 homolog isoform X4

    UniProtKB/TrEMBL
    D3ZSV8
    Related
    ENSRNOP00000077624.2, ENSRNOT00000107056.2

  7. XM_063261988.1 → XP_063118058.1  protein unc-79 homolog isoform X13

    UniProtKB/TrEMBL
    D3ZSV8

  8. XM_063261996.1 → XP_063118066.1  protein unc-79 homolog isoform X21

    UniProtKB/TrEMBL
    A0A8I5ZJJ4

  9. XM_063261981.1 → XP_063118051.1  protein unc-79 homolog isoform X5

    UniProtKB/TrEMBL
    D3ZSV8

  10. XM_063261993.1 → XP_063118063.1  protein unc-79 homolog isoform X19

    UniProtKB/TrEMBL
    A0A8I5ZJJ4

  11. XM_063261984.1 → XP_063118054.1  protein unc-79 homolog isoform X8

    UniProtKB/TrEMBL
    A0A8I5ZJJ4

  12. XM_039112372.2 → XP_038968300.1  protein unc-79 homolog isoform X1

    UniProtKB/TrEMBL
    D3ZSV8
    Conserved Domains (1) summary
    pfam14776
    Location:141 → 672
    UNC-79; Cation-channel complex subunit UNC-79

  13. XM_063261985.1 → XP_063118055.1  protein unc-79 homolog isoform X9

    UniProtKB/TrEMBL
    A0A8I5ZLN3

  14. XM_063261994.1 → XP_063118064.1  protein unc-79 homolog isoform X20

    UniProtKB/TrEMBL
    A0A8I5ZLN3

  15. XM_063261979.1 → XP_063118049.1  protein unc-79 homolog isoform X2

    UniProtKB/TrEMBL
    D3ZSV8

  16. XM_063261982.1 → XP_063118052.1  protein unc-79 homolog isoform X6

    UniProtKB/TrEMBL
    D3ZSV8

  17. XM_063261989.1 → XP_063118059.1  protein unc-79 homolog isoform X15

    UniProtKB/TrEMBL
    D3ZSV8

  18. XM_039112384.2 → XP_038968312.1  protein unc-79 homolog isoform X14

    UniProtKB/TrEMBL
    A0A8I5ZLN3
    Conserved Domains (1) summary
    pfam14776
    Location:141 → 672
    UNC-79; Cation-channel complex subunit UNC-79

  19. XM_063261986.1 → XP_063118056.1  protein unc-79 homolog isoform X11

    UniProtKB/TrEMBL
    D3ZSV8

  20. XM_063261991.1 → XP_063118061.1  protein unc-79 homolog isoform X17

    UniProtKB/TrEMBL
    D3ZSV8

  21. XM_039112381.2 → XP_038968309.1  protein unc-79 homolog isoform X10

    UniProtKB/TrEMBL
    A0A8I5ZJJ4
    Conserved Domains (1) summary
    pfam14776
    Location:88 → 619
    UNC-79; Cation-channel complex subunit UNC-79

  22. XM_063261983.1 → XP_063118053.1  protein unc-79 homolog isoform X7

    UniProtKB/TrEMBL
    A0A8I5ZNV0, D3ZSV8

  23. XM_039112378.2 → XP_038968306.1  protein unc-79 homolog isoform X3

    UniProtKB/TrEMBL
    D3ZSV8
    Related
    ENSRNOP00000079886.2, ENSRNOT00000110508.2
    Conserved Domains (1) summary
    pfam14776
    Location:141 → 672
    UNC-79; Cation-channel complex subunit UNC-79

  24. XM_039112385.2 → XP_038968313.1  protein unc-79 homolog isoform X24

    UniProtKB/TrEMBL
    A0A8I5ZLN3
    Conserved Domains (1) summary
    pfam14776
    Location:141 → 672
    UNC-79; Cation-channel complex subunit UNC-79

  25. XM_063261987.1 → XP_063118057.1  protein unc-79 homolog isoform X12

    UniProtKB/TrEMBL
    D3ZSV8
Nucleotide Protein Strain
Heading Accession and Version

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