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Plekhj1 pleckstrin homology domain containing J1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314634, updated on 2-Nov-2024

Summary

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Official Symbol
Plekhj1provided by RGD
Official Full Name
pleckstrin homology domain containing J1provided by RGD
Primary source
RGD:1307213
See related
EnsemblRapid:ENSRNOG00000075264 AllianceGenome:RGD:1307213
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in endosome organization; receptor recycling; and retrograde transport, endosome to Golgi. Predicted to be active in early endosome; recycling endosome; and trans-Golgi network. Orthologous to human PLEKHJ1 (pleckstrin homology domain containing J1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 293.0), Thymus (RPKM 171.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Plekhj1 in Genome Data Viewer
Location:
7q11
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (9566200..9570993)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (8915492..8920491)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11784314..11786476)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene junctional sarcoplasmic reticulum protein 1 Neighboring gene splicing factor 3A subunit 2 Neighboring gene anti-Mullerian hormone Neighboring gene DOT1 like histone lysine methyltransferase Neighboring gene uncharacterized LOC134479808 Neighboring gene adaptor related protein complex 3 subunit delta 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in endosome organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in receptor recycling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in recycling endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
pleckstrin homology domain-containing family J member 1
Names
pleckstrin homology domain containing, family J member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108072.3 → NP_001101542.1  pleckstrin homology domain-containing family J member 1 isoform 1

    See identical proteins and their annotated locations for NP_001101542.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    B4F791
    Related
    ENSRNOP00000098986.1, ENSRNOT00000123000.1
    Conserved Domains (1) summary
    cd13258
    Location:1 → 112
    PH_PLEKHJ1; Pleckstrin homology domain containing, family J member 1 Pleckstrin homology (PH) domain

  2. NM_001400972.1 → NP_001387901.1  pleckstrin homology domain-containing family J member 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    A6K8G5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    9566200..9570993
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079013.2 → XP_038934941.1  pleckstrin homology domain-containing family J member 1 isoform X3

    Conserved Domains (1) summary
    cl17171
    Location:176 → 227
    PH-like; Pleckstrin homology-like domain

  2. XM_039079014.2 → XP_038934942.1  pleckstrin homology domain-containing family J member 1 isoform X4

    Conserved Domains (1) summary
    cl17171
    Location:176 → 227
    PH-like; Pleckstrin homology-like domain

  3. XM_039079011.2 → XP_038934939.2  pleckstrin homology domain-containing family J member 1 isoform X1

  4. XM_039079012.2 → XP_038934940.2  pleckstrin homology domain-containing family J member 1 isoform X2

  5. XM_039079015.2 → XP_038934943.1  pleckstrin homology domain-containing family J member 1 isoform X5

    Related
    ENSRNOP00000103943.1, ENSRNOT00000160282.1
    Conserved Domains (1) summary
    cd13258
    Location:1 → 112
    PH_PLEKHJ1; Pleckstrin homology domain containing, family J member 1 Pleckstrin homology (PH) domain

  6. XM_063263425.1 → XP_063119495.1  pleckstrin homology domain-containing family J member 1 isoform X7

  7. XM_063263424.1 → XP_063119494.1  pleckstrin homology domain-containing family J member 1 isoform X6

  8. XM_063263426.1 → XP_063119496.1  pleckstrin homology domain-containing family J member 1 isoform X8

Nucleotide Protein Strain
Heading Accession and Version

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