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Zfr2 zinc finger RNA binding protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314639, updated on 17-Aug-2024

Summary

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Official Symbol
Zfr2provided by RGD
Official Full Name
zinc finger RNA binding protein 2provided by RGD
Primary source
RGD:1304737
See related
EnsemblRapid:ENSRNOG00000020416 AllianceGenome:RGD:1304737
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1304737
Summary
Predicted to enable double-stranded RNA binding activity and single-stranded RNA binding activity. Predicted to be located in nucleus. Orthologous to human ZFR2 (zinc finger RNA binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 55.2), Adrenal (RPKM 37.5) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfr2 in Genome Data Viewer
Location:
7q11
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (9117490..9136315, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (8466768..8485593, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11335024..11353743, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L54 Neighboring gene megakaryocyte-associated tyrosine kinase Neighboring gene ATCAY kinesin light chain interacting caytaxin Neighboring gene uncharacterized LOC134479805 Neighboring gene nicotinamide riboside kinase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables double-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables single-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger RNA-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427319.1 → NP_001414248.1  zinc finger RNA-binding protein 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    A0A8I5Y1D0
    Related
    ENSRNOP00000077260.2, ENSRNOT00000118230.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    9117490..9136315 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063263428.1 → XP_063119498.1  zinc finger RNA-binding protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8I5Y1D0, D4A148

  2. XM_039080435.2 → XP_038936363.1  zinc finger RNA-binding protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I5Y1D0
    Conserved Domains (4) summary
    smart00451
    Location:136 → 163
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:138 → 184
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02675
    Location:519 → 770
    DZF; DZF domain
    pfam12874
    Location:333 → 357
    zf-met; Zinc-finger of C2H2 type

  3. XM_063263427.1 → XP_063119497.1  zinc finger RNA-binding protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I5Y1D0

  4. XM_006241033.5 → XP_006241095.1  zinc finger RNA-binding protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006241095.1

    UniProtKB/TrEMBL
    A0A8I5Y1D0
    Conserved Domains (3) summary
    smart00451
    Location:154 → 181
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:156 → 202
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02675
    Location:537 → 788
    DZF; DZF domain

  5. XM_039080436.2 → XP_038936364.1  zinc finger RNA-binding protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A8I5Y1D0
    Conserved Domains (4) summary
    smart00451
    Location:2 → 29
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:4 → 50
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02675
    Location:385 → 636
    DZF; DZF domain
    pfam12874
    Location:199 → 223
    zf-met; Zinc-finger of C2H2 type

  6. XM_039080438.2 → XP_038936366.1  zinc finger RNA-binding protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A8I5Y1D0
    Conserved Domains (5) summary
    smart00451
    Location:177 → 204
    ZnF_U1; U1-like zinc finger
    PHA03247
    Location:20 → 310
    PHA03247; large tegument protein UL36; Provisional
    sd00020
    Location:179 → 225
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02675
    Location:558 → 809
    DZF; DZF domain
    pfam12874
    Location:372 → 396
    zf-met; Zinc-finger of C2H2 type

RNA

  1. XR_010052968.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials