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Actr6 actin related protein 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314718, updated on 10-Oct-2024

Summary

Official Symbol
Actr6provided by RGD
Official Full Name
actin related protein 6provided by RGD
Primary source
RGD:1304609
See related
EnsemblRapid:ENSRNOG00000007875 AllianceGenome:RGD:1304609
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable nucleosome binding activity. Predicted to be involved in histone exchange. Predicted to be located in nucleus. Predicted to be part of Swr1 complex. Orthologous to human ACTR6 (actin related protein 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 211.9), Brain (RPKM 105.5) and 9 other tissues See more
Orthologs
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Genomic context

See Actr6 in Genome Data Viewer
Location:
7q13
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (26037574..26058362, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (24150250..24171057, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (30377369..30397922, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479656 Neighboring gene uncharacterized LOC134479655 Neighboring gene bridge-like lipid transfer protein family member 3B Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1B Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables nucleosome binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in nucleolus organization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of Swr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
actin-related protein 6
Names
ARP6 actin-related protein 6 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108081.1NP_001101551.1  actin-related protein 6

    See identical proteins and their annotated locations for NP_001101551.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473960
    UniProtKB/TrEMBL
    B2RYQ1, F7F615
    Related
    ENSRNOP00000092687.2, ENSRNOT00000118790.2
    Conserved Domains (1) summary
    smart00268
    Location:2394
    ACTIN; Actin

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    26037574..26058362 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006241243.3XP_006241305.2  actin-related protein 6 isoform X1

  2. XM_039079042.2XP_038934970.1  actin-related protein 6 isoform X2

    Conserved Domains (1) summary
    smart00268
    Location:10312
    ACTIN; Actin
  3. XM_039079041.1XP_038934969.1  actin-related protein 6 isoform X2

    Conserved Domains (1) summary
    smart00268
    Location:10312
    ACTIN; Actin