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Ankrd49 ankyrin repeat domain 49 [ Rattus norvegicus (Norway rat) ]

Gene ID: 315434, updated on 2-Nov-2024

Summary

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Official Symbol
Ankrd49provided by RGD
Official Full Name
ankyrin repeat domain 49provided by RGD
Primary source
RGD:1311759
See related
EnsemblRapid:ENSRNOG00000009233 AllianceGenome:RGD:1311759
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311759
Summary
Predicted to be involved in positive regulation of DNA-templated transcription. Orthologous to human ANKRD49 (ankyrin repeat domain 49). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 84.7), Spleen (RPKM 80.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ankrd49 in Genome Data Viewer
Location:
8q12
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (19908968..19913656, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (11627512..11632200, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (13299556..13304244, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094082 Neighboring gene similar to human chromosome 11 open reading frame 97 Neighboring gene MRE11 homolog, double strand break repair nuclease Neighboring gene G protein-coupled receptor 83 Neighboring gene uncharacterized LOC102549408

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. {gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice. Blau CA, et al. J Biol Chem, 2005 Nov 4. PMID 16131492
  2. Cloning and characterization of a potential transcriptional activator of human gamma-globin genes. Yang Y, et al. Blood Cells Mol Dis, 2001 Jan-Feb. PMID 11162141
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in positive regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ankyrin repeat domain-containing protein 49

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126283.1 → NP_001119755.1  ankyrin repeat domain-containing protein 49

    See identical proteins and their annotated locations for NP_001119755.1

    Status: PROVISIONAL

    Source sequence(s)
    BC161982
    UniProtKB/TrEMBL
    A6JNA1, B1WC29
    Related
    ENSRNOP00000012583.4, ENSRNOT00000012583.6
    Conserved Domains (3) summary
    sd00045
    Location:78 → 105
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:78 → 170
    Ank_2; Ankyrin repeats (3 copies)
    pfam13857
    Location:160 → 216
    Ank_5; Ankyrin repeats (many copies)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    19908968..19913656 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242525.4 → XP_006242587.1  ankyrin repeat domain-containing protein 49 isoform X1

    See identical proteins and their annotated locations for XP_006242587.1

    UniProtKB/TrEMBL
    A6JNA1, B1WC29
    Conserved Domains (3) summary
    sd00045
    Location:78 → 105
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:78 → 170
    Ank_2; Ankyrin repeats (3 copies)
    pfam13857
    Location:160 → 216
    Ank_5; Ankyrin repeats (many copies)

  2. XM_039081350.2 → XP_038937278.1  ankyrin repeat domain-containing protein 49 isoform X1

    UniProtKB/TrEMBL
    A6JNA1, B1WC29
    Conserved Domains (3) summary
    sd00045
    Location:78 → 105
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:78 → 170
    Ank_2; Ankyrin repeats (3 copies)
    pfam13857
    Location:160 → 216
    Ank_5; Ankyrin repeats (many copies)
Nucleotide Protein Strain
Heading Accession and Version

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