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mAChR-C muscarinic Acetylcholine Receptor, C-type [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31626, updated on 2-Nov-2024

Summary

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Official Symbol
mAChR-Cprovided by FlyBase
Official Full Name
muscarinic Acetylcholine Receptor, C-typeprovided by FlyBase
Primary source
FLYBASE:FBgn0029909
Locus tag
Dmel_CG12796
See related
AllianceGenome:FB:FBgn0029909
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG12796; Dmel\CG12796
Summary
Enables G protein-coupled acetylcholine receptor activity. Involved in G protein-coupled acetylcholine receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See mAChR-C in Genome Data Viewer
Location:
6D4-6D4; 1-18 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (6831397..6832684, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (6725430..6726717, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene xiantuan Neighboring gene Ataxin 1 Neighboring gene no-on-and-no-off transient C Neighboring gene uncharacterized protein Neighboring gene TATA element modulatory factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The neurobiology and evolution of cannabinoid signalling. Elphick MR, et al. Philos Trans R Soc Lond B Biol Sci, 2001 Mar 29. PMID 11316486, Free PMC Article
  2. Localization of muscarinic acetylcholine receptor-dependent rhythm-generating modules in the Drosophila larval locomotor network. Jonaitis J, et al. J Neurophysiol, 2022 Apr 1. PMID 35294308, Free PMC Article
  3. Pharmacological identification of cholinergic receptor subtypes: modulation of locomotion and neural circuit excitability in Drosophila larvae. Malloy CA, et al. Neuroscience, 2019 Jul 15. PMID 31102763
  4. A new family of insect muscarinic acetylcholine receptors. Xia RY, et al. Insect Mol Biol, 2016 Aug. PMID 27003873
  5. Muscarinic acetylcholine receptor activation synergizes the knockdown and toxicity of GABA-gated chloride channel insecticides. Xie N, et al. Pest Manag Sci, 2022 Nov. PMID 35841135, Free PMC Article

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables G protein-coupled acetylcholine receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables G protein-coupled acetylcholine receptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables G protein-coupled amine receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled acetylcholine receptor signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in G protein-coupled receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IC
Inferred by Curator
more info
 PubMed 

General protein information

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Preferred Names
muscarinic acetylcholine Receptor, C-type
Names
CG12796-PA
mAChR-C-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    6831397..6832684 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132130.2 → NP_572358.1  muscarinic acetylcholine Receptor, C-type [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572358.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A109NH66, Q9W3V5
    Related
    FBpp0070934
    Conserved Domains (2) summary
    pfam00001
    Location:67 → 321
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:61 → 332
    7tm_4; Olfactory receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W3V5 Q9W3V5

Gene LinkOut

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