Ndufa10l1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ndufa10l1provided by RGD
Official Full Name: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 1provided by RGD
Primary source: RGD:1589745
See related: EnsemblRapid:ENSRNOG00000062245 AllianceGenome:RGD:1589745
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: CI-42kD; Ndufa10
Summary: Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial matrix. Predicted to be part of respiratory chain complex I. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 22. Orthologous to human NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Note: The correct placement for Ndufa10l is on Rno6 with a single exon structure. The highly similar paralog Ndufa10 (geneID:678759) was incorrectly placed at the same location on the reference assembly for NCBI Build 4.1. The correct placement for Ndufa10 is on Rno9. [17 Jun 2014]
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Genomic context

Location:: 6q21

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (65606866..65608299, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (59879819..59881252, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (62796951..62798384, complement)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Ndufa10 (e-PCR), detects polymorphism
- UniSTS:527437

RH129838 (e-PCR)
- UniSTS:213126

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial respiratory chain complex I assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex I	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like

Names: Complex I-42kD; NADH dehydrogenase 1 alpha subcomplex 10-like protein; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; NADH-ubiquinone oxidoreductase 42 kDa subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_182671.2 → NP_872612.1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like

See identical proteins and their annotated locations for NP_872612.1

Status: VALIDATED

Source sequence(s)

AY260163

UniProtKB/TrEMBL

A0A1W2Q6F8, A0A8L2QBL2

Related

ENSRNOP00000076258.1, ENSRNOT00000093200.3

Conserved Domains (1) summary

cd02030
Location:59 → 277

NDUO42; NADH:Ubiquinone oxioreductase, 42 kDa (NDUO42) is a family of proteins that are highly similar to deoxyribonucleoside kinases (dNK). Members of this family have been identified as one of the subunits of NADH:Ubiquinone oxioreductase (complex I), a ...