U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rab33a RAB33A, member RAS oncogene family [ Rattus norvegicus (Norway rat) ]

Gene ID: 317580, updated on 2-Nov-2024

Summary

Official Symbol
Rab33aprovided by RGD
Official Full Name
RAB33A, member RAS oncogene familyprovided by RGD
Primary source
RGD:1563280
See related
EnsemblRapid:ENSRNOG00000006698 AllianceGenome:RGD:1563280
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563280
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in antigen processing and presentation and autophagosome assembly. Predicted to be active in Golgi apparatus and endosome. Orthologous to human RAB33A (RAB33A, member RAS oncogene family). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 250.3), Brain (RPKM 89.0) and 2 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Rab33a in Genome Data Viewer
Location:
Xq36
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (132572133..132584255)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (127694219..127706378)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (135348799..135360204)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene E74 like ETS transcription factor 4 Neighboring gene apoptosis inducing factor, mitochondria associated 1 Neighboring gene zinc finger protein 280C Neighboring gene solute carrier family 25 member 14 Neighboring gene G protein-coupled receptor 119

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in Rab protein signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in antigen processing and presentation ISO
Inferred from Sequence Orthology
more info
 
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
ras-related protein Rab-33A
Names
RAB33A, member of RAS oncogene family

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108257.1NP_001101727.1  ras-related protein Rab-33A

    See identical proteins and their annotated locations for NP_001101727.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473991
    UniProtKB/TrEMBL
    A6JMQ7, D3ZCU8
    Related
    ENSRNOP00000008868.2, ENSRNOT00000008868.6
    Conserved Domains (2) summary
    cd04115
    Location:35204
    Rab33B_Rab33A; Rab GTPase family 33 includes Rab33A and Rab33B
    smart00175
    Location:37205
    RAB; Rab subfamily of small GTPases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    132572133..132584255
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039099851.2XP_038955779.1  ras-related protein Rab-33A isoform X1

    Conserved Domains (1) summary
    cl38936
    Location:3594
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases