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Magec2 MAGE family member C2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 317590, updated on 28-Oct-2024

Summary

Official Symbol
Magec2provided by RGD
Official Full Name
MAGE family member C2provided by RGD
Primary source
RGD:1563272
See related
EnsemblRapid:ENSRNOG00000026265 AllianceGenome:RGD:1563272
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of ubiquitin-protein transferase activity; and protein catabolic process. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human MAGEC2 (MAGE family member C2). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Restricted expression toward (RPKM 36.5) See more
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Genomic context

See Magec2 in Genome Data Viewer
Location:
Xq36
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (145646856..145651730)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (140610610..140615484)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (145353959..145362427)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene LDOC1, regulator of NFKB signaling Neighboring gene ribosomal RNA processing 12, pseudogene 1 Neighboring gene SPANX family, member N4 like Neighboring gene uncharacterized LOC102546822 Neighboring gene uncharacterized LOC134484001

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC114529

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein LOC317590
Names
melanoma antigen family C, 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025713.1NP_001020884.1  uncharacterized protein LOC317590

    See identical proteins and their annotated locations for NP_001020884.1

    Status: PREDICTED

    Source sequence(s)
    BC097464
    UniProtKB/TrEMBL
    A0A8I5YBY6, A6K513, Q4QR72
    Related
    ENSRNOP00000034773.4, ENSRNOT00000033723.6
    Conserved Domains (1) summary
    pfam01454
    Location:224379
    MAGE; MAGE family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    145646856..145651730
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)