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ttn.2 - titin, tandem duplicate 2

A structural constituent of muscle. Acts upstream of or within several processes, including heart contraction; myofibril assembly; and striated muscle tissue development. Is active in centriole; cytoplasm; and nucleus. Is expressed in several structures, including cardiovascular system; mesoderm; musculature system; somite; and testis. Used to study atrial fibrillation and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple) and myopathy (multiple). Orthologous to human TTN (titin). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa