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su(r) - suppressor of rudimentary

Predicted to enable NADP binding activity; dihydropyrimidine dehydrogenase (NADP+) activity; and uracil binding activity. Involved in 'de novo' pyrimidine nucleobase biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; dihydropyrimidine dehydrogenase deficiency; and pancreatic cancer. Orthologous to human DPYD (dihydropyrimidine dehydrogenase). [provided by Alliance of Genome Resources, Oct 2024]

Genes similar to su(r)

NCBI Orthologs

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Species Gene Architecture aa