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H2ac19 H2A clustered histone 19 [ Mus musculus (house mouse) ]

Gene ID: 319192, updated on 28-Oct-2024

Summary

Official Symbol
H2ac19provided by MGI
Official Full Name
H2A clustered histone 19provided by MGI
Primary source
MGI:MGI:2448283
See related
Ensembl:ENSMUSG00000063954 AllianceGenome:MGI:2448283
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2a-614; H2a-615; Hist2h2aa2
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. [provided by RefSeq, Aug 2015]
Orthologs
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Genomic context

See H2ac19 in Genome Data Viewer
Location:
3 F2.1; 3 41.69 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (96147065..96147638, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (96239779..96240374, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1023 Neighboring gene H2B clustered histone 21 Neighboring gene H3 clustered histone 15 Neighboring gene STARR-seq mESC enhancer starr_08410 Neighboring gene H2A clustered histone 18 Neighboring gene H3 clustered histone 14

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC107211

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of chromatin IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of nucleosome IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
histone H2A type 2-A
Names
histone cluster 2, H2aa2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178212.4NP_835584.1  histone H2A type 2-A

    See identical proteins and their annotated locations for NP_835584.1

    Status: VALIDATED

    Source sequence(s)
    AC125099
    Consensus CDS
    CCDS57241.1
    UniProtKB/Swiss-Prot
    Q6GSS7, Q811M3
    UniProtKB/TrEMBL
    A0AUV1, B2RWH3
    Related
    ENSMUSP00000100581.4, ENSMUST00000074976.8
    Conserved Domains (1) summary
    PTZ00017
    Location:1130
    PTZ00017; histone H2A; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    96147065..96147638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)