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Zfp944 zinc finger protein 944 [ Mus musculus (house mouse) ]

Gene ID: 319615, updated on 28-Oct-2024

Summary

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Official Symbol
Zfp944provided by MGI
Official Full Name
zinc finger protein 944provided by MGI
Primary source
MGI:MGI:2442394
See related
Ensembl:ENSMUSG00000033972 AllianceGenome:MGI:2442394
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6330416L07Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in early conceptus; inner cell mass; and oocyte. [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in CNS E18 (RPKM 3.8), CNS E14 (RPKM 3.3) and 28 other tissues See more
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Genomic context

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See Zfp944 in Genome Data Viewer
Location:
17 A3.3; 17 11.4 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (22556964..22580409, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (22337983..22361428, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52309 Neighboring gene zinc finger protein 994 Neighboring gene STARR-seq mESC enhancer starr_42025 Neighboring gene STARR-positive B cell enhancer ABC_E4195 Neighboring gene STARR-seq mESC enhancer starr_42027 Neighboring gene predicted gene 7072 Neighboring gene STARR-seq mESC enhancer starr_42028 Neighboring gene predicted gene, 53992 Neighboring gene STARR-positive B cell enhancer ABC_E5576 Neighboring gene STARR-seq mESC enhancer starr_42030 Neighboring gene zinc finger protein 758 Neighboring gene STARR-seq mESC enhancer starr_42031 Neighboring gene STARR-positive B cell enhancer ABC_E5577 Neighboring gene STARR-seq mESC enhancer starr_42032 Neighboring gene zinc finger protein 946 Neighboring gene STARR-seq mESC enhancer starr_42034 Neighboring gene eukaryotic translation elongation factor 1 gamma pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  3. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC117948

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC319615

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355280.1 → NP_001342209.1  uncharacterized protein LOC319615

    Status: VALIDATED

    Source sequence(s)
    AC117244
    Consensus CDS
    CCDS50000.1
    UniProtKB/TrEMBL
    E9PUS4
    Conserved Domains (4) summary
    COG5048
    Location:321 → 484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241 → 261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:253 → 278
    zf-H2C2_2; Zinc-finger double domain

  2. NM_176962.4 → NP_795936.2  uncharacterized protein LOC319615

    See identical proteins and their annotated locations for NP_795936.2

    Status: VALIDATED

    Source sequence(s)
    AC117244, BE133041, CJ187522
    Consensus CDS
    CCDS50000.1
    UniProtKB/TrEMBL
    E9PUS4
    Related
    ENSMUSP00000111197.3, ENSMUST00000115535.3
    Conserved Domains (4) summary
    COG5048
    Location:321 → 484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241 → 261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:253 → 278
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    22556964..22580409 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249840.2 → XP_030105700.1  uncharacterized protein LOC319615 isoform X3

    Conserved Domains (3) summary
    COG5048
    Location:283 → 446
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:203 → 223
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:215 → 240
    zf-H2C2_2; Zinc-finger double domain

  2. XM_036160643.1 → XP_036016536.1  uncharacterized protein LOC319615 isoform X2

    UniProtKB/TrEMBL
    E9PUS4
    Conserved Domains (4) summary
    COG5048
    Location:321 → 484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241 → 261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:253 → 278
    zf-H2C2_2; Zinc-finger double domain

  3. XM_030249838.2 → XP_030105698.1  uncharacterized protein LOC319615 isoform X2

    UniProtKB/TrEMBL
    E9PUS4
    Conserved Domains (4) summary
    COG5048
    Location:321 → 484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241 → 261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:253 → 278
    zf-H2C2_2; Zinc-finger double domain

  4. XM_036160640.1 → XP_036016533.1  uncharacterized protein LOC319615 isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:341 → 504
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:261 → 281
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:33 → 72
    KRAB; KRAB box
    pfam13465
    Location:273 → 298
    zf-H2C2_2; Zinc-finger double domain

  5. XM_036160641.1 → XP_036016534.1  uncharacterized protein LOC319615 isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:341 → 504
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:261 → 281
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:33 → 72
    KRAB; KRAB box
    pfam13465
    Location:273 → 298
    zf-H2C2_2; Zinc-finger double domain

  6. XM_036160642.1 → XP_036016535.1  uncharacterized protein LOC319615 isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:341 → 504
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:261 → 281
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:33 → 72
    KRAB; KRAB box
    pfam13465
    Location:273 → 298
    zf-H2C2_2; Zinc-finger double domain

  7. XM_030249836.2 → XP_030105696.1  uncharacterized protein LOC319615 isoform X2

    UniProtKB/TrEMBL
    E9PUS4
    Conserved Domains (4) summary
    COG5048
    Location:321 → 484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241 → 261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:253 → 278
    zf-H2C2_2; Zinc-finger double domain

  8. XM_030249835.2 → XP_030105695.1  uncharacterized protein LOC319615 isoform X2

    UniProtKB/TrEMBL
    E9PUS4
    Conserved Domains (4) summary
    COG5048
    Location:321 → 484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241 → 261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:253 → 278
    zf-H2C2_2; Zinc-finger double domain

  9. XM_030249837.2 → XP_030105697.1  uncharacterized protein LOC319615 isoform X2

    UniProtKB/TrEMBL
    E9PUS4
    Conserved Domains (4) summary
    COG5048
    Location:321 → 484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241 → 261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:253 → 278
    zf-H2C2_2; Zinc-finger double domain

  10. XM_036160639.1 → XP_036016532.1  uncharacterized protein LOC319615 isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:341 → 504
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:261 → 281
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:33 → 72
    KRAB; KRAB box
    pfam13465
    Location:273 → 298
    zf-H2C2_2; Zinc-finger double domain

  11. XM_030249834.2 → XP_030105694.1  uncharacterized protein LOC319615 isoform X2

    UniProtKB/TrEMBL
    E9PUS4
    Conserved Domains (4) summary
    COG5048
    Location:321 → 484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:241 → 261
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:253 → 278
    zf-H2C2_2; Zinc-finger double domain

  12. XM_036160638.1 → XP_036016531.1  uncharacterized protein LOC319615 isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:341 → 504
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:261 → 281
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:33 → 72
    KRAB; KRAB box
    pfam13465
    Location:273 → 298
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

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