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Krt26 keratin 26 [ Mus musculus (house mouse) ]

Gene ID: 320864, updated on 2-Nov-2024

Summary

Official Symbol
Krt26provided by MGI
Official Full Name
keratin 26provided by MGI
Primary source
MGI:MGI:2444913
See related
Ensembl:ENSMUSG00000075570 AllianceGenome:MGI:2444913
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Krt25b; 4732407F15Rik
Summary
Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Is expressed in vibrissa epidermal component. Orthologous to human KRT26 (keratin 26). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Krt26 in Genome Data Viewer
Location:
11 D; 11 62.92 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (99219310..99228791, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (99328484..99337965, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32385 Neighboring gene keratin 24 Neighboring gene STARR-seq mESC enhancer starr_30703 Neighboring gene keratin 25 Neighboring gene keratin 27 Neighboring gene keratin 28

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in epithelial cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermediate filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
keratin, type I cytoskeletal 26
Names
CK-26
K26
cytokeratin-26
keratin 25B
type I inner root sheath-specific keratin-K25irs2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033397.5NP_001028569.2  keratin, type I cytoskeletal 26

    See identical proteins and their annotated locations for NP_001028569.2

    Status: VALIDATED

    Source sequence(s)
    AK132445, AK162718
    Consensus CDS
    CCDS25378.1
    UniProtKB/Swiss-Prot
    Q3TRJ4, Q3V1H8
    Related
    ENSMUSP00000098051.3, ENSMUST00000100482.3
    Conserved Domains (2) summary
    pfam00038
    Location:79394
    Filament; Intermediate filament protein
    pfam09455
    Location:215416
    Cas_DxTHG; CRISPR-associated (Cas) DxTHG family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    99219310..99228791 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)