U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zmynd12 zinc finger, MYND domain containing 12 [ Mus musculus (house mouse) ]

Gene ID: 332934, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Zmynd12provided by MGI
Official Full Name
zinc finger, MYND domain containing 12provided by MGI
Primary source
MGI:MGI:2140259
See related
Ensembl:ENSMUSG00000070806 AllianceGenome:MGI:2140259
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be involved in sperm axoneme assembly. Predicted to be located in sperm flagellum. Orthologous to human ZMYND12 (zinc finger MYND-type containing 12). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in testis adult (RPKM 37.9), ovary adult (RPKM 3.4) and 2 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Zmynd12 in Genome Data Viewer
Location:
4 D2.1; 4 55.38 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (119279881..119311096)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (119422611..119453899)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 30 Neighboring gene lactate dehydrogenase A, pseudogene 2 Neighboring gene STARR-seq mESC enhancer starr_11233 Neighboring gene phosphopantothenoylcysteine synthetase Neighboring gene STARR-positive B cell enhancer ABC_E2708 Neighboring gene ribosomal modification protein rimK-like family member A Neighboring gene STARR-seq mESC enhancer starr_11235 Neighboring gene cyclin H pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. ZMYND12 serves as an IDAd subunit that is essential for sperm motility in mice. Wang C, et al. Cell Mol Life Sci, 2024 Jul 27. PMID 39066891, Free PMC Article
  2. Role of the ANKMY2-FKBP38 axis in regulation of the Sonic hedgehog (Shh) signaling pathway. Saita S, et al. J Biol Chem, 2014 Sep 12. PMID 25077969, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ZMYND12 serves as an IDAd subunit that is essential for sperm motility in mice.
    Title: ZMYND12 serves as an IDAd subunit that is essential for sperm motility in mice.
Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in flagellated sperm motility ISO
Inferred from Sequence Orthology
more info
  
involved_in sperm axoneme assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in sperm flagellum ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger MYND domain-containing protein 12

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014900.2 → NP_001014900.2  zinc finger MYND domain-containing protein 12

    See identical proteins and their annotated locations for NP_001014900.2

    Status: VALIDATED

    Source sequence(s)
    AL645563, BC147848
    Consensus CDS
    CCDS18582.1
    UniProtKB/TrEMBL
    A2BGJ5, Q56GB0
    Related
    ENSMUSP00000092414.5, ENSMUST00000094819.5
    Conserved Domains (3) summary
    sd00006
    Location:132 → 162
    TPR; TPR repeat [structural motif]
    pfam01753
    Location:17 → 54
    zf-MYND; MYND finger
    pfam13424
    Location:92 → 156
    TPR_12; Tetratricopeptide repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    119279881..119311096
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503191.4 → XP_006503254.1  zinc finger MYND domain-containing protein 12 isoform X1

    Conserved Domains (3) summary
    sd00006
    Location:132 → 162
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:92 → 156
    TPR_12; Tetratricopeptide repeat
    pfam01753
    Location:17 → 54
    zf-MYND; MYND finger
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools