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oaf out at first [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33435, updated on 2-Nov-2024

Summary

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Official Symbol
oafprovided by FlyBase
Official Full Name
out at firstprovided by FlyBase
Primary source
FLYBASE:FBgn0011818
Locus tag
Dmel_CG9884
See related
AllianceGenome:FB:FBgn0011818
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9884; Dmel\CG9884; l(2)22Fb; l(2)ND1; tnd
Summary
Is expressed in several structures, including ganglia; germline cell; gonad; mesoderm; and sensory nervous system primordium. Orthologous to human OAF (out at first homolog). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See oaf in Genome Data Viewer
Location:
22F4-22F4; 2-6 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2492955..2498846)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2492955..2498846)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45286 Neighboring gene SLY-1 homologous Neighboring gene long non-coding RNA:CR44607 Neighboring gene antisense RNA:CR46069 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Developmental regulation of eukaryotic gene loci: which cis-regulatory information is required? Bonifer C. Trends Genet, 2000 Jul. PMID 10858661
  2. Reprogrammed genetic decoding in cellular gene expression. Namy O, et al. Mol Cell, 2004 Jan 30. PMID 14759362
  3. Regulatory autonomy and molecular characterization of the Drosophila out at first gene. Bergstrom DE, et al. Genetics, 1995 Mar. PMID 7768442, Free PMC Article
  4. An extensive 3' cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-beta family in Drosophila. Blackman RK, et al. Development, 1991 Mar. PMID 1908769
  5. Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Teumer A, et al. Nat Commun, 2019 Sep 11. PMID 31511532, Free PMC Article

See all (56) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
out at first
Names
CG9884-PA
CG9884-PB
CG9884-PC
CG9884-PD
near dpp complementation group 1
oaf-PA
oaf-PB
oaf-PC
oaf-PD
transcript near decapentaplegic
transcript-near-decapentaplegic

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2492955..2498846
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057692.2 → NP_477040.1  out at first, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477040.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A4V013, Q6NP33
    Related
    FBpp0077456, FBtr0077777
    Conserved Domains (1) summary
    pfam14941
    Location:81 → 332
    OAF; Transcriptional regulator, Out at first

  2. NM_175949.1 → NP_787963.2  out at first, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_787963.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24556, Q86CS3, Q9NLA6
    Related
    FBpp0077459, FBtr0077780
    Conserved Domains (1) summary
    pfam14941
    Location:81 → 332
    OAF; Transcriptional regulator, Out at first

  3. NM_164489.2 → NP_722815.1  out at first, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722815.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A4V013, Q6NP33
    Related
    FBpp0077457
    Conserved Domains (1) summary
    pfam14941
    Location:81 → 332
    OAF; Transcriptional regulator, Out at first

  4. NM_164490.1 → NP_722816.1  out at first, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722816.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A4V013, Q6NP33
    Related
    FBpp0077458, FBtr0077779
    Conserved Domains (1) summary
    pfam14941
    Location:81 → 332
    OAF; Transcriptional regulator, Out at first
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A4V013 A4V013
Q9NLA6.2 Q9NLA6

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