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spx2 SPX/EXS domain-containing protein [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 3361154, updated on 18-Sep-2024

Summary

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Official Symbol
spx2
Official Full Name
SPX/EXS domain-containing protein
Primary source
PomBase:SPCC1827.07c
Locus tag
SPOM_SPCC1827.07C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPCP1E11.01c
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Genomic context

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See spx2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003421.2 (2388317..2391285, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene RNA-binding protein NIFK Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene aspartate semialdehyde dehydrogenase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ark1/Prk1 family protein kinase Ppk38

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast. Schwer B, et al. mBio, 2022 Feb 22. PMID 35012333, Free PMC Article
  2. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
  3. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast.
    Title: Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables inositol hexakisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphate transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to phosphate starvation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphate ion export across plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphate ion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane EXP
Inferred from Experiment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SPX/EXS domain-containing protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    2388317..2391285 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023540.4 → NP_588554.2  SPX/EXS domain-containing protein [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588554.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74979, Q9UU86
    Conserved Domains (3) summary
    COG5408
    Location:1 → 272
    COG5408; SPX domain-containing protein [Signal transduction mechanisms]
    COG5409
    Location:271 → 641
    COG5409; EXS domain-containing protein [Signal transduction mechanisms]
    cd14475
    Location:2 → 207
    SPX_SYG1_like; SPX domain of the yeast plasma protein Syg1 and related proteins
Nucleotide Protein
Heading Accession and Version

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