U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

swi3 replication fork protection complex subunit Swi3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 3361323, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
swi3
Official Full Name
replication fork protection complex subunit Swi3
Primary source
PomBase:SPBC30D10.04
Locus tag
SPOM_SPBC30D10.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See swi3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003423.3 (3090859..3091856, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene biotin-protein ligase Neighboring gene U6 snRNP-associated protein Lsm4 Neighboring gene ncRNA Neighboring gene sepiapterin reductase Neighboring gene chaperone protein Mzm1 Neighboring gene ncRNA Neighboring gene IMP 5'-nucleotidase Neighboring gene ncRNA Neighboring gene transcription corepressor

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. RNase-sensitive DNA modification(s) initiates S. pombe mating-type switching. Vengrova S, et al. Genes Dev, 2004 Apr 1. PMID 15059961, Free PMC Article
  2. Biochemical interactions between proteins and mat1 cis-acting sequences required for imprinting in fission yeast. Lee BS, et al. Mol Cell Biol, 2004 Nov. PMID 15509785, Free PMC Article
  3. Swi1 associates with chromatin through the DDT domain and recruits Swi3 to preserve genomic integrity. Noguchi C, et al. PLoS One, 2012. PMID 22952839, Free PMC Article
  4. Fission yeast Swi1-Swi3 complex facilitates DNA binding of Mrc1. Tanaka T, et al. J Biol Chem, 2010 Dec 17. PMID 20924116, Free PMC Article
  5. swi1 and swi3 perform imprinting, pausing, and termination of DNA replication in S. pombe. Dalgaard JZ, et al. Cell, 2000 Sep 15. PMID 11030618

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Fission yeast Swi1-Swi3 complex facilitates DNA binding of Mrc1.
    Title: Fission yeast Swi1-Swi3 complex facilitates DNA binding of Mrc1.
  2. RFC(Ctf18) and the Swi1-Swi3 complex function in separate and redundant pathways essential for replication fork stabilization to facilitate sister chromatid cohesion in fission yeast.
    Title: RFCCtf18 and the Swi1-Swi3 complex function in separate and redundant pathways required for the stabilization of replication forks to facilitate sister chromatid cohesion in Schizosaccharomyces pombe.
  3. Hsk1-Dfp1/Him1 and Swi1-Swi3 complexes have interrelated roles in stabilization of arrested replication forks
    Title: Hsk1-Dfp1/Him1, the Cdc7-Dbf4 kinase in Schizosaccharomyces pombe, associates with Swi1, a component of the replication fork protection complex.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables Y-form DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables double-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA replication checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in gene conversion at mating-type locus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mating-type locus imprinting IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in replication fork arrest IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in replication fork arrest IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in replication fork arrest at mating type locus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in replication fork processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitochondrion HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of replication fork protection complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of replication fork protection complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
replication fork protection complex subunit Swi3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3090859..3091856 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022202.3 → NP_001018832.1  replication fork protection complex subunit Swi3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_001018832.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14350, Q6IUU5
    Conserved Domains (1) summary
    pfam07962
    Location:53 → 131
    Swi3; Replication Fork Protection Component Swi3
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials