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fgfr2 - fibroblast growth factor receptor 2

Enables fibroblast growth factor binding activity. Acts upstream of or within several processes, including cell proliferation in midbrain; determination of left/right symmetry; and pectoral fin development. Predicted to be located in Golgi apparatus; cytoplasmic vesicle; and membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including cranium; digestive system; mesoderm; nervous system; and trunk vasculature. Human ortholog(s) of this gene implicated in several diseases, including Beare-Stevenson cutis gyrata syndrome; breast cancer (multiple); gastrointestinal system cancer (multiple); reproductive organ cancer (multiple); and synostosis (multiple). Orthologous to human FGFR2 (fibroblast growth factor receptor 2). [provided by Alliance of Genome Resources, Oct 2024]

Genes similar to fgfr2

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Species Gene Architecture aa