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otx5 - orthodenticle homolog 5

Enables sequence-specific DNA binding activity. Acts upstream of or within circadian regulation of gene expression and positive regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in forebrain; optic vesicle; and visual system. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 7 and cone-rod dystrophy 2. Orthologous to human CRX (cone-rod homeobox). [provided by Alliance of Genome Resources, Oct 2024]

Genes similar to otx5

NCBI Orthologs

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Species Gene Architecture aa