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hal-2 Coiled-coil domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 3564857, updated on 2-Nov-2024

Summary

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Official Symbol
hal-2
Official Full Name
Coiled-coil domain-containing protein
Primary source
WormBase:WBGene00011819
Locus tag
CELE_T16H12.11
See related
AllianceGenome:WB:WBGene00011819
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Located in nucleoplasm. Is expressed in germ cell. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See hal-2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (10087188..10088931, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene General transcription factor IIH subunit 2 Neighboring gene Speckle-type POZ protein homolog Neighboring gene Kelch repeat-containing protein kel-10

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. HAL-2 promotes homologous pairing during Caenorhabditis elegans meiosis by antagonizing inhibitory effects of synaptonemal complex precursors. Zhang W, et al. PLoS Genet, 2012. PMID 22912597, Free PMC Article
  2. Automated and customizable quantitative image analysis of whole Caenorhabditis elegans germlines. Toraason E, et al. Genetics, 2021 Mar 31. PMID 33772283, Free PMC Article
  3. Spatial Regulation of Polo-Like Kinase Activity During Caenorhabditis elegans Meiosis by the Nucleoplasmic HAL-2/HAL-3 Complex. Roelens B, et al. Genetics, 2019 Sep. PMID 31345995, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. hal-2 mutants exhibit multiple meiotic prophase defects. HAL-2/HAL-3 protein complex regulates localization and activity of meiotic Polo-like kinases.
    Title: Spatial Regulation of Polo-Like Kinase Activity During Caenorhabditis elegans Meiosis by the Nucleoplasmic HAL-2/HAL-3 Complex.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Coiled-coil domain-containing protein
NP_001379406.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    10087188..10088931 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392184.1 → NP_001379406.1  Coiled-coil domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YWU3
Nucleotide Protein
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